Title |
Thyroid Involvement in Hepatitis C Virus-Infected Patients with/without Mixed Cryoglobulinemia
|
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Published in |
Frontiers in endocrinology, July 2017
|
DOI | 10.3389/fendo.2017.00159 |
Pubmed ID | |
Authors |
Clodoveo Ferri, Michele Colaci, Poupak Fallahi, Silvia Martina Ferrari, Alessandro Antonelli, Dilia Giuggioli |
Abstract |
Thyroid involvement is a common condition that can be recorded during the natural course of different systemic rheumatic diseases, including the mixed cryoglobulinemia (MC) syndrome or cryoglobulinemic vasculitis. MC is triggered by hepatitis C virus (HCV) chronic infection in the majority of cases; it represents the prototype of autoimmune-lymphoproliferative disorders complicating a significant proportion of patients with chronic HCV infection. HCV is both hepato- and lymphotropic virus responsible for a great number of autoimmune/lymphoproliferative and/or neoplastic disorders. The complex of HCV-related hepatic and extrahepatic manifestations, including MC and thyroid involvement, may be termed "HCV syndrome." Here, we describe the prevalence and clinico-serological characteristics of thyroid involvement, mainly autoimmune thyroiditis and papillary thyroid cancer, in patients with HCV syndrome with or without cryoglobulinemic vasculitis. |
X Demographics
Geographical breakdown
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Switzerland | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 29 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Professor | 5 | 17% |
Student > Master | 4 | 14% |
Student > Ph. D. Student | 3 | 10% |
Student > Bachelor | 2 | 7% |
Student > Doctoral Student | 2 | 7% |
Other | 5 | 17% |
Unknown | 8 | 28% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 12 | 41% |
Immunology and Microbiology | 3 | 10% |
Agricultural and Biological Sciences | 2 | 7% |
Biochemistry, Genetics and Molecular Biology | 2 | 7% |
Sports and Recreations | 1 | 3% |
Other | 1 | 3% |
Unknown | 8 | 28% |