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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The Emerging Facets of Non-Cancerous Warburg Effect
|
|---|---|
| Published in |
Frontiers in endocrinology, October 2017
|
| DOI | 10.3389/fendo.2017.00279 |
| Pubmed ID | |
| Authors |
Alyaa M. Abdel-Haleem, Nathan E. Lewis, Neema Jamshidi, Katsuhiko Mineta, Xin Gao, Takashi Gojobori |
| Abstract |
The Warburg effect (WE), or aerobic glycolysis, is commonly recognized as a hallmark of cancer and has been extensively studied for potential anti-cancer therapeutics development. Beyond cancer, the WE plays an important role in many other cell types involved in immunity, angiogenesis, pluripotency, and infection by pathogens (e.g., malaria). Here, we review the WE in non-cancerous context as a "hallmark of rapid proliferation." We observe that the WE operates in rapidly dividing cells in normal and pathological states that are triggered by internal and external cues. Aerobic glycolysis is also the preferred metabolic program in the cases when robust transient responses are needed. We aim to draw attention to the potential of computational modeling approaches in systematic characterization of common metabolic features beyond the WE across physiological and pathological conditions. Identification of metabolic commonalities across various diseases may lead to successful repurposing of drugs and biomarkers. |
X Demographics
The data shown below were collected from the profiles of 16 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 19% |
| Switzerland | 2 | 13% |
| Canada | 2 | 13% |
| Spain | 1 | 6% |
| Germany | 1 | 6% |
| United Kingdom | 1 | 6% |
| Unknown | 6 | 38% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 10 | 63% |
| Scientists | 6 | 38% |
Mendeley readers
The data shown below were compiled from readership statistics for 132 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 132 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 34 | 26% |
| Researcher | 20 | 15% |
| Student > Master | 16 | 12% |
| Student > Bachelor | 13 | 10% |
| Student > Doctoral Student | 8 | 6% |
| Other | 17 | 13% |
| Unknown | 24 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 40 | 30% |
| Agricultural and Biological Sciences | 20 | 15% |
| Immunology and Microbiology | 11 | 8% |
| Medicine and Dentistry | 10 | 8% |
| Engineering | 5 | 4% |
| Other | 16 | 12% |
| Unknown | 30 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 January 2021.
All research outputs
#3,840,405
of 25,806,080 outputs
Outputs from Frontiers in endocrinology
#1,273
of 13,284 outputs
Outputs of similar age
#67,320
of 339,528 outputs
Outputs of similar age from Frontiers in endocrinology
#19
of 114 outputs
Altmetric has tracked 25,806,080 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 13,284 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.1. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 339,528 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 114 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 83% of its contemporaries.