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X Demographics
Mendeley readers
Attention Score in Context
| Title |
E2F1, a Novel Regulator of Metabolism
|
|---|---|
| Published in |
Frontiers in endocrinology, November 2017
|
| DOI | 10.3389/fendo.2017.00311 |
| Pubmed ID | |
| Authors |
Pierre-Damien Denechaud, Lluis Fajas, Albert Giralt |
| Abstract |
In the past years, several lines of evidence have shown that cell cycle regulatory proteins also can modulate metabolic processes. The transcription factor E2F1 is a central player involved in cell cycle progression, DNA-damage response, and apoptosis. Its crucial role in the control of cell fate has been extensively studied and reviewed before; however, here, we focus on the participation of E2F1 in the regulation of metabolism. We summarize recent findings about the cell cycle-independent roles of E2F1 in various tissues that contribute to global metabolic homeostasis and highlight that E2F1 activity is increased during obesity. Finally, coming back to the pivotal role of E2F1 in cancer development, we discuss how E2F1 links cell cycle progression with different metabolic adaptations required for cell growth and survival. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 1 | 33% |
| Switzerland | 1 | 33% |
| Unknown | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 177 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 177 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 40 | 23% |
| Student > Master | 21 | 12% |
| Researcher | 18 | 10% |
| Student > Doctoral Student | 13 | 7% |
| Student > Bachelor | 11 | 6% |
| Other | 19 | 11% |
| Unknown | 55 | 31% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 66 | 37% |
| Agricultural and Biological Sciences | 19 | 11% |
| Medicine and Dentistry | 11 | 6% |
| Chemistry | 4 | 2% |
| Immunology and Microbiology | 3 | 2% |
| Other | 15 | 8% |
| Unknown | 59 | 33% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 January 2018.
All research outputs
#17,292,294
of 25,382,440 outputs
Outputs from Frontiers in endocrinology
#5,292
of 13,021 outputs
Outputs of similar age
#216,885
of 339,332 outputs
Outputs of similar age from Frontiers in endocrinology
#53
of 115 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,021 research outputs from this source. They receive a mean Attention Score of 4.9. This one has gotten more attention than average, scoring higher than 55% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 339,332 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 115 others from the same source and published within six weeks on either side of this one. This one is in the 49th percentile – i.e., 49% of its contemporaries scored the same or lower than it.