Title |
Mitochondrial Dynamics in Type 2 Diabetes and Cancer
|
---|---|
Published in |
Frontiers in endocrinology, April 2018
|
DOI | 10.3389/fendo.2018.00211 |
Pubmed ID | |
Authors |
Michelle Williams, M. Cecilia Caino |
Abstract |
Mitochondria are bioenergetic, biosynthetic, and signaling organelles that control various aspects of cellular and organism homeostasis. Quality control mechanisms are in place to ensure maximal mitochondrial function and metabolic homeostasis at the cellular level. Dysregulation of these pathways is a common theme in human disease. In this mini-review, we discuss how alterations of the mitochondrial network influences mitochondrial function, focusing on the molecular regulators of mitochondrial dynamics (organelle's shape and localization). We highlight similarities and critical differences in the mitochondrial network of cancer and type 2 diabetes, which may be relevant for treatment of these diseases. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 4 | 40% |
Netherlands | 1 | 10% |
Colombia | 1 | 10% |
Switzerland | 1 | 10% |
Unknown | 3 | 30% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 10 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 52 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 12 | 23% |
Student > Bachelor | 6 | 12% |
Student > Doctoral Student | 5 | 10% |
Student > Master | 5 | 10% |
Researcher | 4 | 8% |
Other | 7 | 13% |
Unknown | 13 | 25% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 15 | 29% |
Agricultural and Biological Sciences | 6 | 12% |
Medicine and Dentistry | 5 | 10% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 4% |
Immunology and Microbiology | 2 | 4% |
Other | 7 | 13% |
Unknown | 15 | 29% |