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The Big Entity of New RNA World: Long Non-Coding RNAs in Microvascular Complications of Diabetes

Overview of attention for article published in Frontiers in endocrinology, June 2018
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Title
The Big Entity of New RNA World: Long Non-Coding RNAs in Microvascular Complications of Diabetes
Published in
Frontiers in endocrinology, June 2018
DOI 10.3389/fendo.2018.00300
Pubmed ID
Authors

Satish K. Raut, Madhu Khullar

Abstract

A major part of the genome is known to be transcribed into non-protein coding RNAs (ncRNAs), such as microRNA and long non-coding RNA (lncRNA). The importance of ncRNAs is being increasingly recognized in physiological and pathological processes. lncRNAs are a novel class of ncRNAs that do not code for proteins and are important regulators of gene expression. In the past, these molecules were thought to be transcriptional "noise" with low levels of evolutionary conservation. However, recent studies provide strong evidence indicating that lncRNAs are (i) regulated during various cellular processes, (ii) exhibit cell type-specific expression, (iii) localize to specific organelles, and (iv) associated with human diseases. Emerging evidence indicates an aberrant expression of lncRNAs in diabetes and diabetes-related microvascular complications. In the present review, we discuss the current state of knowledge of lncRNAs, their genesis from genome, and the mechanism of action of individual lncRNAs in the pathogenesis of microvascular complications of diabetes and therapeutic approaches.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 43 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 43 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 7 16%
Researcher 5 12%
Unspecified 4 9%
Student > Postgraduate 4 9%
Student > Ph. D. Student 4 9%
Other 8 19%
Unknown 11 26%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 9 21%
Medicine and Dentistry 9 21%
Unspecified 4 9%
Agricultural and Biological Sciences 3 7%
Pharmacology, Toxicology and Pharmaceutical Science 2 5%
Other 2 5%
Unknown 14 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 June 2018.
All research outputs
#20,663,600
of 25,382,440 outputs
Outputs from Frontiers in endocrinology
#6,739
of 13,021 outputs
Outputs of similar age
#267,325
of 342,821 outputs
Outputs of similar age from Frontiers in endocrinology
#148
of 222 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,021 research outputs from this source. They receive a mean Attention Score of 4.9. This one is in the 35th percentile – i.e., 35% of its peers scored the same or lower than it.
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