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Impact of Maternal Age on Oocyte and Embryo Competence

Overview of attention for article published in Frontiers in endocrinology, June 2018
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (76th percentile)
  • High Attention Score compared to outputs of the same age and source (84th percentile)

Citations

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288 Dimensions

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424 Mendeley
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1 CiteULike
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Title
Impact of Maternal Age on Oocyte and Embryo Competence
Published in
Frontiers in endocrinology, June 2018
DOI 10.3389/fendo.2018.00327
Pubmed ID
Authors

Danilo Cimadomo, Gemma Fabozzi, Alberto Vaiarelli, Nicolò Ubaldi, Filippo Maria Ubaldi, Laura Rienzi

Abstract

The overall success of human reproduction, either spontaneously or after IVF, is highly dependent upon maternal age. The main reasons for age-related infertility include reduced ovarian reserve and decreased oocyte/embryo competence due to aging insults, especially concerning an increased incidence of aneuploidies and possibly decreased mitochondrial activity. Age-related chromosomal abnormalities mainly arise because of meiotic impairments during oogenesis, following flawed chromosome segregation patterns such as non-disjunction, premature separation of sister chromatids, or the recent reverse segregation. In this review, we briefly discuss the main mechanisms putatively impaired by aging in the oocytes and the deriving embryos. We also report the main strategies proposed to improve the management of advanced maternal age women in IVF: fertility preservation through oocyte cryopreservation to prevent aging; optimization of the ovarian stimulation and enhancement of embryo selection to limit its effects; and oocyte donation to circumvent its consequences.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 424 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 424 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 61 14%
Student > Master 48 11%
Student > Ph. D. Student 38 9%
Researcher 27 6%
Other 22 5%
Other 64 15%
Unknown 164 39%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 89 21%
Medicine and Dentistry 78 18%
Agricultural and Biological Sciences 28 7%
Nursing and Health Professions 11 3%
Unspecified 7 2%
Other 31 7%
Unknown 180 42%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 October 2022.
All research outputs
#4,575,167
of 25,385,509 outputs
Outputs from Frontiers in endocrinology
#1,328
of 13,021 outputs
Outputs of similar age
#81,575
of 343,092 outputs
Outputs of similar age from Frontiers in endocrinology
#32
of 207 outputs
Altmetric has tracked 25,385,509 research outputs across all sources so far. Compared to these this one has done well and is in the 81st percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 13,021 research outputs from this source. They receive a mean Attention Score of 4.9. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 343,092 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 76% of its contemporaries.
We're also able to compare this research output to 207 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.