Title |
No Guts, No Loss: Toward the Ideal Treatment for Obesity in the Twenty-First Century
|
---|---|
Published in |
Frontiers in endocrinology, August 2018
|
DOI | 10.3389/fendo.2018.00442 |
Pubmed ID | |
Authors |
David C. D. Hope, Tricia M. M. Tan, Stephen R. Bloom |
Abstract |
Over the last century, our knowledge of the processes which control appetite and weight regulation has developed significantly. The understanding of where gut hormones fit into the control of energy homeostasis in addition to the rapid advancement of pharmacotherapeutics has paved the way for the development of novel gut hormone analogs to target weight loss. Currently, bariatric surgery remains the most efficacious treatment for obesity. The emergence of gut hormone analogs may provide a useful non-surgical addition to the armamentarium in treating obesity. Simply targeting single gut hormone pathways may be insufficiently efficacious, and combination/multiple-agonist approaches may be necessary to obtain the results required for clear clinical impact. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Canada | 3 | 27% |
United States | 2 | 18% |
Spain | 1 | 9% |
Brazil | 1 | 9% |
Switzerland | 1 | 9% |
Unknown | 3 | 27% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 9 | 82% |
Scientists | 2 | 18% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 73 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 11 | 15% |
Student > Ph. D. Student | 8 | 11% |
Researcher | 8 | 11% |
Student > Postgraduate | 7 | 10% |
Student > Master | 5 | 7% |
Other | 10 | 14% |
Unknown | 24 | 33% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 19 | 26% |
Pharmacology, Toxicology and Pharmaceutical Science | 6 | 8% |
Biochemistry, Genetics and Molecular Biology | 6 | 8% |
Agricultural and Biological Sciences | 5 | 7% |
Nursing and Health Professions | 5 | 7% |
Other | 6 | 8% |
Unknown | 26 | 36% |