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Epigenetic Memory in Mammals

Overview of attention for article published in Frontiers in Genetics, January 2011
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (94th percentile)
  • High Attention Score compared to outputs of the same age and source (98th percentile)

Mentioned by

news
1 news outlet
blogs
1 blog
twitter
4 X users
peer_reviews
1 peer review site

Citations

dimensions_citation
72 Dimensions

Readers on

mendeley
184 Mendeley
citeulike
1 CiteULike
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Title
Epigenetic Memory in Mammals
Published in
Frontiers in Genetics, January 2011
DOI 10.3389/fgene.2011.00028
Pubmed ID
Authors

Zoë Migicovsky, Igor Kovalchuk

Abstract

Epigenetic information can be passed on from one generation to another via DNA methylation, histone modifications, and changes in small RNAs, a process called epigenetic memory. During a mammal's lifecycle epigenetic reprogramming, or the resetting of most epigenetic marks, occurs twice. The first instance of reprogramming occurs in primordial germ cells and the second occurs following fertilization. These processes may be both passive and active. In order for epigenetic inheritance to occur the epigenetic modifications must be able to escape reprogramming. There are several examples supporting this non-Mendelian mechanism of inheritance including the prepacking of early developmental genes in histones instead of protamines in sperm, genomic imprinting via methylation marks, the retention of CenH3 in mammalian sperm and the inheritance of piwi-associated interfering RNAs. The ability of mammals to pass on epigenetic information to their progeny provides clear evidence that inheritance is not restricted to DNA sequence and epigenetics plays a key role in producing viable offspring.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 184 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 4 2%
United States 2 1%
Canada 2 1%
Serbia 1 <1%
Unknown 175 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 41 22%
Researcher 38 21%
Student > Bachelor 25 14%
Student > Master 22 12%
Professor 12 7%
Other 28 15%
Unknown 18 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 68 37%
Biochemistry, Genetics and Molecular Biology 34 18%
Medicine and Dentistry 20 11%
Neuroscience 15 8%
Psychology 4 2%
Other 12 7%
Unknown 31 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 18. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 August 2022.
All research outputs
#1,923,529
of 24,541,341 outputs
Outputs from Frontiers in Genetics
#416
of 13,229 outputs
Outputs of similar age
#10,672
of 189,532 outputs
Outputs of similar age from Frontiers in Genetics
#2
of 57 outputs
Altmetric has tracked 24,541,341 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 13,229 research outputs from this source. They receive a mean Attention Score of 3.7. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 189,532 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 57 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 98% of its contemporaries.