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X Demographics
Mendeley readers
Attention Score in Context
| Title |
MicroRNA Control of Invasion and Metastasis Pathways
|
|---|---|
| Published in |
Frontiers in Genetics, January 2011
|
| DOI | 10.3389/fgene.2011.00058 |
| Pubmed ID | |
| Authors |
Rahul Sreekumar, Berna S. Sayan, Alex H. Mirnezami, A. Emre Sayan |
| Abstract |
Despite recent advances, cancer remains a leading cause of death worldwide. In developed countries, the incidence of colorectal and breast cancer has been stable, but no improvement in prognosis has been observed if the patient presents with metastases at diagnosis. This fact highlights the importance of therapeutic approaches targeting cellular invasion and metastasis programs as the next step in cancer treatment. During carcinoma progression a process called epithelial-mesenchymal transition (EMT) results in enhanced invasion and motility which is directly linked with loss of epithelial polarity and epithelial junctions, migration permissive cytoskeleton alterations, and the acquisition of mesenchymal properties. The recent discovery of microRNAs (miRNAs) controlling key cellular pathways has opened a new era in understanding how EMT pathways are modulated. In this review, we classify EMT regulating proteins according to their cellular localization (membrane, cytoplasmic, and nuclear), and summarize the current knowledge on how they are controlled by miRNAs and propose potential miRNAs for the transcripts that may control their expression. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 60 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| China | 1 | 2% |
| Germany | 1 | 2% |
| Unknown | 58 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 19 | 32% |
| Student > Ph. D. Student | 11 | 18% |
| Researcher | 10 | 17% |
| Other | 5 | 8% |
| Student > Doctoral Student | 4 | 7% |
| Other | 9 | 15% |
| Unknown | 2 | 3% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 25 | 42% |
| Medicine and Dentistry | 15 | 25% |
| Biochemistry, Genetics and Molecular Biology | 12 | 20% |
| Immunology and Microbiology | 2 | 3% |
| Unspecified | 1 | 2% |
| Other | 1 | 2% |
| Unknown | 4 | 7% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 February 2012.
All research outputs
#14,142,788
of 22,662,201 outputs
Outputs from Frontiers in Genetics
#3,880
of 11,727 outputs
Outputs of similar age
#136,259
of 180,278 outputs
Outputs of similar age from Frontiers in Genetics
#24
of 58 outputs
Altmetric has tracked 22,662,201 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 11,727 research outputs from this source. They receive a mean Attention Score of 3.7. This one has gotten more attention than average, scoring higher than 62% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 180,278 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 23rd percentile – i.e., 23% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 58 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.