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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Unraveling the Mystery of Cancer by Secretory microRNA: Horizontal microRNA Transfer between Living Cells
|
|---|---|
| Published in |
Frontiers in Genetics, January 2012
|
| DOI | 10.3389/fgene.2011.00097 |
| Pubmed ID | |
| Authors |
Nobuyoshi Kosaka, Takahiro Ochiya |
| Abstract |
microRNAs (miRNAs) have been identified as a fine-tuner in a wide array of biological processes, including development, organogenesis, metabolism, and homeostasis. Deregulation of miRNAs causes diseases, especially cancer. This occurs through a variety of mechanisms, such as genetic alterations, epigenetic regulation, or altered expression of transcription factors, which target miRNAs. Recently, it was discovered that extracellular miRNAs circulate in the blood of both healthy and diseased patients. Since RNase is abundant in the bloodstream, most of the secretory miRNAs are contained in apoptotic bodies, microvesicles, and exosomes or bound to the RNA-binding proteins. However, the secretory mechanism and biological function, as well as the significance of extracellular miRNAs, remain largely unclear. In this article, we summarize the latest and most significant discoveries in recent peer-reviewed research on secretory miRNA involvement in many aspects of physiological and pathological conditions, with a special focus on cancer. In addition, we discuss a new aspect of cancer research that is revealed by the emergence of "secretory miRNA." |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 1 | 33% |
| Switzerland | 1 | 33% |
| Japan | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 67% |
| Scientists | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 103 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Netherlands | 2 | 2% |
| United Kingdom | 2 | 2% |
| Germany | 1 | <1% |
| Portugal | 1 | <1% |
| Austria | 1 | <1% |
| Uruguay | 1 | <1% |
| Brazil | 1 | <1% |
| Belgium | 1 | <1% |
| Unknown | 93 | 90% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 31 | 30% |
| Student > Ph. D. Student | 18 | 17% |
| Student > Master | 12 | 12% |
| Professor > Associate Professor | 10 | 10% |
| Professor | 6 | 6% |
| Other | 19 | 18% |
| Unknown | 7 | 7% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 55 | 53% |
| Medicine and Dentistry | 19 | 18% |
| Biochemistry, Genetics and Molecular Biology | 16 | 16% |
| Neuroscience | 2 | 2% |
| Computer Science | 1 | <1% |
| Other | 3 | 3% |
| Unknown | 7 | 7% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 February 2012.
All research outputs
#13,128,189
of 22,662,201 outputs
Outputs from Frontiers in Genetics
#2,918
of 11,727 outputs
Outputs of similar age
#145,149
of 244,049 outputs
Outputs of similar age from Frontiers in Genetics
#92
of 255 outputs
Altmetric has tracked 22,662,201 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 11,727 research outputs from this source. They receive a mean Attention Score of 3.7. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 244,049 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 255 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 62% of its contemporaries.