Title |
When One and One Gives More than Two: Challenges and Opportunities of Integrative Omics
|
---|---|
Published in |
Frontiers in Genetics, January 2012
|
DOI | 10.3389/fgene.2011.00105 |
Pubmed ID | |
Authors |
Hyungwon Choi, Norman Pavelka |
Abstract |
Since the dawn of the post-genomic era a myriad of novel high-throughput technologies have been developed that are capable of measuring thousands of biological molecules at once, giving rise to various "omics" platforms. These advances offer the unique opportunity to study how individual parts of a biological system work together to produce emerging phenotypes. Today, many research laboratories are moving toward applying multiple omics platforms to analyze the same biological samples. In addition, network information of interacting molecules is being incorporated more and more into the analysis and interpretation of these multiple omics datasets, which provides novel ways to integrate multiple layers of heterogeneous biological information into a single coherent picture. Here, we provide a perspective on how such recent "integrative omics" efforts are likely going to shift biological paradigms once again, and what challenges lie ahead. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Switzerland | 1 | 33% |
South Africa | 1 | 33% |
Unknown | 1 | 33% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 67% |
Scientists | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 4 | 4% |
United Kingdom | 3 | 3% |
Mexico | 2 | 2% |
France | 1 | <1% |
Sweden | 1 | <1% |
Germany | 1 | <1% |
Russia | 1 | <1% |
Belgium | 1 | <1% |
Unknown | 93 | 87% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 25 | 23% |
Student > Ph. D. Student | 24 | 22% |
Student > Master | 14 | 13% |
Professor > Associate Professor | 10 | 9% |
Professor | 7 | 7% |
Other | 16 | 15% |
Unknown | 11 | 10% |
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Biochemistry, Genetics and Molecular Biology | 11 | 10% |
Computer Science | 10 | 9% |
Medicine and Dentistry | 8 | 7% |
Immunology and Microbiology | 3 | 3% |
Other | 12 | 11% |
Unknown | 17 | 16% |