Title |
Dark Matter RNA: Existence, Function, and Controversy
|
---|---|
Published in |
Frontiers in Genetics, January 2012
|
DOI | 10.3389/fgene.2012.00060 |
Pubmed ID | |
Authors |
Philipp Kapranov, Georges St. Laurent |
Abstract |
The mysteries surrounding the ∼97-98% of the human genome that does not encode proteins have long captivated imagination of scientists. Does the protein-coding, 2-3% of the genome carry the 97-98% as a mere passenger and neutral "cargo" on the evolutionary path, or does the latter have biological function? On one side of the debate, many commentaries have referred to the non-coding portion of the genome as "selfish" or "junk" DNA (Orgel and Crick, 1980), while on the other side, authors have argued that it contains the real blueprint for organismal development (Penman, 1995; Mattick, 2003), and the mechanisms of developmental complexity. Thus, this question could be referred to without much exaggeration as the most important issue in genetics today. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 25% |
United Kingdom | 1 | 25% |
Egypt | 1 | 25% |
Australia | 1 | 25% |
Demographic breakdown
Type | Count | As % |
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Scientists | 4 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 2 | 2% |
Netherlands | 2 | 2% |
Germany | 1 | <1% |
France | 1 | <1% |
Japan | 1 | <1% |
Unknown | 117 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 38 | 31% |
Researcher | 24 | 19% |
Student > Master | 16 | 13% |
Student > Doctoral Student | 6 | 5% |
Student > Bachelor | 5 | 4% |
Other | 15 | 12% |
Unknown | 20 | 16% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 52 | 42% |
Biochemistry, Genetics and Molecular Biology | 25 | 20% |
Chemistry | 6 | 5% |
Medicine and Dentistry | 4 | 3% |
Engineering | 4 | 3% |
Other | 12 | 10% |
Unknown | 21 | 17% |