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X Demographics
Mendeley readers
Attention Score in Context
| Title |
MicroRNAs as Novel Biomarkers in Colorectal Cancer
|
|---|---|
| Published in |
Frontiers in Genetics, January 2012
|
| DOI | 10.3389/fgene.2012.00180 |
| Pubmed ID | |
| Authors |
Sonja Hrašovec, Damjan Glavač |
| Abstract |
MicroRNAs (miRNAs) play an important role in various physiologic and developmental processes and in the initiation and progression of cancer. This class of small, non-coding RNAs critically regulate gene expression at the post-transcriptional level and evidence suggests that they may function as both oncogenes and tumor suppressors. Colorectal cancer (CRC) is a major healthcare concern worldwide and in order to reduce CRC related deaths, research is aimed into the search for some novel screening approaches. In this sense, miRNAs are rapidly emerging as a novel class of biomarkers, with good potential as diagnostic and therapeutic targets. This review summarizes the recent findings of the clinicopathological relevance that miRNAs have in CRC initiation, development, and progress, highlighting their potential diagnostic, prognostic, and therapeutic use in CRC, focusing on the group of microsatellite instable and the group of hypermethylated CRCs, as well as discussing future prospects. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| France | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 50% |
| Members of the public | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 60 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 60 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 15 | 25% |
| Researcher | 14 | 23% |
| Student > Ph. D. Student | 10 | 17% |
| Student > Bachelor | 7 | 12% |
| Student > Doctoral Student | 2 | 3% |
| Other | 5 | 8% |
| Unknown | 7 | 12% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 16 | 27% |
| Agricultural and Biological Sciences | 15 | 25% |
| Medicine and Dentistry | 13 | 22% |
| Business, Management and Accounting | 2 | 3% |
| Immunology and Microbiology | 2 | 3% |
| Other | 6 | 10% |
| Unknown | 6 | 10% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 October 2012.
All research outputs
#14,153,088
of 22,681,577 outputs
Outputs from Frontiers in Genetics
#3,889
of 11,749 outputs
Outputs of similar age
#153,462
of 244,101 outputs
Outputs of similar age from Frontiers in Genetics
#116
of 255 outputs
Altmetric has tracked 22,681,577 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 11,749 research outputs from this source. They receive a mean Attention Score of 3.7. This one has gotten more attention than average, scoring higher than 62% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 244,101 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 35th percentile – i.e., 35% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 255 others from the same source and published within six weeks on either side of this one. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.