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Exploiting Gene Expression Variation to Capture Gene-Environment Interactions for Disease

Overview of attention for article published in Frontiers in Genetics, January 2013
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  • Good Attention Score compared to outputs of the same age and source (67th percentile)

Mentioned by

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2 Wikipedia pages

Citations

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23 Dimensions

Readers on

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46 Mendeley
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1 CiteULike
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Title
Exploiting Gene Expression Variation to Capture Gene-Environment Interactions for Disease
Published in
Frontiers in Genetics, January 2013
DOI 10.3389/fgene.2012.00228
Pubmed ID
Authors

Youssef Idaghdour, Philip Awadalla

Abstract

Gene-environment interactions have long been recognized as a fundamental concept in evolutionary, quantitative, and medical genetics. In the genomics era, study of how environment and genome interact to shape gene expression variation is relevant to understanding the genetic architecture of complex phenotypes. While genetic analysis of gene expression variation focused on main effects, little is known about the extent of interaction effects implicating regulatory variants and their consequences on transcriptional variation. Here we survey the current state of the concept of transcriptional gene-environment interactions and discuss its utility for mapping disease phenotypes in light of the insights gained from genome-wide association studies of gene expression.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 46 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 46 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 14 30%
Researcher 10 22%
Professor > Associate Professor 5 11%
Student > Doctoral Student 3 7%
Student > Master 2 4%
Other 5 11%
Unknown 7 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 17 37%
Medicine and Dentistry 7 15%
Biochemistry, Genetics and Molecular Biology 6 13%
Computer Science 2 4%
Neuroscience 2 4%
Other 2 4%
Unknown 10 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 October 2015.
All research outputs
#7,454,951
of 22,790,780 outputs
Outputs from Frontiers in Genetics
#2,428
of 11,761 outputs
Outputs of similar age
#84,270
of 281,013 outputs
Outputs of similar age from Frontiers in Genetics
#103
of 319 outputs
Altmetric has tracked 22,790,780 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 11,761 research outputs from this source. They receive a mean Attention Score of 3.7. This one has done well, scoring higher than 78% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 281,013 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 319 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.