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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Role of Glyoxalase 1 (Glo1) and methylglyoxal (MG) in behavior: recent advances and mechanistic insights
|
|---|---|
| Published in |
Frontiers in Genetics, January 2012
|
| DOI | 10.3389/fgene.2012.00250 |
| Pubmed ID | |
| Authors |
Margaret G. Distler, Abraham A. Palmer |
| Abstract |
Glyoxalase 1 (GLO1) is a ubiquitous cellular enzyme that participates in the detoxification of methylglyoxal (MG), a cytotoxic byproduct of glycolysis that induces protein modification (advanced glycation end-products, AGEs), oxidative stress, and apoptosis. The concentration of MG is elevated under high-glucose conditions, such as diabetes. As such, GLO1 and MG have been implicated in the pathogenesis of diabetic complications. Recently, findings have linked GLO1 to numerous behavioral phenotypes, including psychiatric diseases (anxiety, depression, schizophrenia, and autism) and pain. This review highlights GLO1's association with behavioral phenotypes, describes recent discoveries that have elucidated the underlying mechanisms, and identifies opportunities for future research. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 50% |
| Switzerland | 1 | 25% |
| Unknown | 1 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 75% |
| Practitioners (doctors, other healthcare professionals) | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 141 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 2% |
| Japan | 2 | 1% |
| Peru | 1 | <1% |
| Italy | 1 | <1% |
| Poland | 1 | <1% |
| Unknown | 133 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 27 | 19% |
| Student > Ph. D. Student | 22 | 16% |
| Student > Bachelor | 16 | 11% |
| Student > Master | 14 | 10% |
| Student > Doctoral Student | 9 | 6% |
| Other | 24 | 17% |
| Unknown | 29 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 37 | 26% |
| Biochemistry, Genetics and Molecular Biology | 20 | 14% |
| Medicine and Dentistry | 16 | 11% |
| Neuroscience | 7 | 5% |
| Psychology | 5 | 4% |
| Other | 18 | 13% |
| Unknown | 38 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 23. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 February 2022.
All research outputs
#1,403,416
of 23,025,074 outputs
Outputs from Frontiers in Genetics
#280
of 12,073 outputs
Outputs of similar age
#10,050
of 245,484 outputs
Outputs of similar age from Frontiers in Genetics
#9
of 255 outputs
Altmetric has tracked 23,025,074 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 12,073 research outputs from this source. They receive a mean Attention Score of 3.7. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 245,484 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 255 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.