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The Intersection of Aging, Longevity Pathways, and Learning and Memory in C. elegans

Overview of attention for article published in Frontiers in Genetics, January 2012
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Title
The Intersection of Aging, Longevity Pathways, and Learning and Memory in C. elegans
Published in
Frontiers in Genetics, January 2012
DOI 10.3389/fgene.2012.00259
Pubmed ID
Authors

Geneva M. Stein, Coleen T. Murphy

Abstract

Our understanding of the molecular and genetic regulation of aging and longevity has been greatly augmented through studies using the small model system, C. elegans. It is important to test whether mutations that result in a longer life span also extend the health span of the organism, rather than simply prolonging an aged state. C. elegans can learn and remember both associated and non-associated stimuli, and many of these learning and memory paradigms are subject to regulation by longevity pathways. One of the more distressing results of aging is cognitive decline, and while no gross physical defects in C. elegans sensory neurons have been identified, the organism does lose the ability to perform both simple and complex learned behaviors with age. Here we review what is known about the effects of longevity pathways and the decline of these complex learned behaviors with age, and we highlight outstanding questions in the field.

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X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 156 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 3 2%
Israel 2 1%
Belgium 2 1%
Singapore 1 <1%
Hungary 1 <1%
Unknown 147 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 41 26%
Researcher 23 15%
Student > Master 20 13%
Student > Bachelor 17 11%
Student > Doctoral Student 9 6%
Other 23 15%
Unknown 23 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 69 44%
Biochemistry, Genetics and Molecular Biology 30 19%
Engineering 9 6%
Neuroscience 6 4%
Medicine and Dentistry 4 3%
Other 12 8%
Unknown 26 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 January 2019.
All research outputs
#17,671,894
of 22,687,320 outputs
Outputs from Frontiers in Genetics
#6,015
of 11,752 outputs
Outputs of similar age
#191,346
of 244,125 outputs
Outputs of similar age from Frontiers in Genetics
#169
of 255 outputs
Altmetric has tracked 22,687,320 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 11,752 research outputs from this source. They receive a mean Attention Score of 3.7. This one is in the 40th percentile – i.e., 40% of its peers scored the same or lower than it.
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We're also able to compare this research output to 255 others from the same source and published within six weeks on either side of this one. This one is in the 29th percentile – i.e., 29% of its contemporaries scored the same or lower than it.