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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Exosomal miRNAs as Biomarkers for Prostate Cancer
|
|---|---|
| Published in |
Frontiers in Genetics, January 2013
|
| DOI | 10.3389/fgene.2013.00036 |
| Pubmed ID | |
| Authors |
Nina Pettersen Hessvik, Kirsten Sandvig, Alicia Llorente |
| Abstract |
miRNAs are small non-coding RNAs that finely regulate gene expression in cells. Alterations in miRNA expression have been associated with development of cancer, and miRNAs are now being investigated as biomarkers for cancer as well as other diseases. Recently, miRNAs have been found outside cells in body fluids. Extracellular miRNAs exist in different forms - associated with Ago2 proteins, loaded into extracellular vesicles (exosomes, microvesicles, or apoptotic bodies) or into high density lipoprotein particles. These extracellular miRNAs are probably products of distinct cellular processes, and might therefore play different roles. However, their functions in vivo are currently unknown. In spite of this, they are considered as promising, non-invasive diagnostic, and prognostic tools. Prostate cancer is the most common cancer in men in the Western world, but the currently used biomarker (prostate specific antigen) has low specificity. Therefore, novel biomarkers are highly needed. In this review we will discuss possible biological functions of extracellular miRNAs, as well as the potential use of miRNAs from extracellular vesicles as biomarkers for prostate cancer. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 2 | 67% |
| France | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 67% |
| Scientists | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 146 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 1% |
| Germany | 1 | <1% |
| Brazil | 1 | <1% |
| Iran, Islamic Republic of | 1 | <1% |
| Denmark | 1 | <1% |
| Spain | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 138 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 35 | 24% |
| Researcher | 26 | 18% |
| Student > Bachelor | 18 | 12% |
| Student > Master | 17 | 12% |
| Professor > Associate Professor | 8 | 5% |
| Other | 19 | 13% |
| Unknown | 23 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 42 | 29% |
| Biochemistry, Genetics and Molecular Biology | 32 | 22% |
| Medicine and Dentistry | 27 | 18% |
| Engineering | 4 | 3% |
| Chemistry | 4 | 3% |
| Other | 7 | 5% |
| Unknown | 30 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 April 2013.
All research outputs
#13,509,057
of 23,305,591 outputs
Outputs from Frontiers in Genetics
#3,038
of 12,324 outputs
Outputs of similar age
#158,905
of 283,648 outputs
Outputs of similar age from Frontiers in Genetics
#127
of 319 outputs
Altmetric has tracked 23,305,591 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 12,324 research outputs from this source. They receive a mean Attention Score of 3.7. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 283,648 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 319 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 59% of its contemporaries.