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The household contact study design for genetic epidemiological studies of infectious diseases

Overview of attention for article published in Frontiers in Genetics, January 2013
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Title
The household contact study design for genetic epidemiological studies of infectious diseases
Published in
Frontiers in Genetics, January 2013
DOI 10.3389/fgene.2013.00061
Pubmed ID
Authors

Catherine M. Stein, Noémi B. Hall, LaShaunda L. Malone, Ezekiel Mupere

Abstract

MOST GENETIC EPIDEMIOLOGICAL STUDY DESIGNS FALL INTO ONE OF TWO CATEGORIES: family based and population-based (case-control). However, recent advances in statistical genetics call for study designs that combine these two approaches. We describe the household contact study design as we have applied it in our several years of study of the epidemiology of tuberculosis. Though we highlight its applicability for genetic epidemiological studies of infectious diseases, there are many facets of this design that are appealing for modern genetic studies, including the simultaneous enrollment of related and unrelated individuals, closely and distantly related individuals, collection of extensive epidemiologic and phenotypic data, and evaluation of effects of shared environment and gene by environment interaction. These study design characteristics are particularly appealing for current sequencing studies.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 33 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 33 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 10 30%
Researcher 5 15%
Student > Ph. D. Student 4 12%
Unspecified 2 6%
Professor 2 6%
Other 5 15%
Unknown 5 15%
Readers by discipline Count As %
Medicine and Dentistry 11 33%
Agricultural and Biological Sciences 5 15%
Nursing and Health Professions 3 9%
Immunology and Microbiology 2 6%
Unspecified 2 6%
Other 4 12%
Unknown 6 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 April 2013.
All research outputs
#20,191,579
of 22,708,120 outputs
Outputs from Frontiers in Genetics
#8,529
of 11,755 outputs
Outputs of similar age
#248,737
of 280,717 outputs
Outputs of similar age from Frontiers in Genetics
#263
of 319 outputs
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