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Micronuclei in genotoxicity assessment: from genetics to epigenetics and beyond

Overview of attention for article published in Frontiers in Genetics, January 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (96th percentile)
  • High Attention Score compared to outputs of the same age and source (96th percentile)

Mentioned by

news
1 news outlet
blogs
1 blog
twitter
12 X users
patent
1 patent
peer_reviews
1 peer review site
wikipedia
1 Wikipedia page

Readers on

mendeley
526 Mendeley
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Title
Micronuclei in genotoxicity assessment: from genetics to epigenetics and beyond
Published in
Frontiers in Genetics, January 2013
DOI 10.3389/fgene.2013.00131
Pubmed ID
Authors

Lidiya Luzhna, Palak Kathiria, Olga Kovalchuk

Abstract

Micronuclei (MN) are extra-nuclear bodies that contain damaged chromosome fragments and/or whole chromosomes that were not incorporated into the nucleus after cell division. MN can be induced by defects in the cell repair machinery and accumulation of DNA damages and chromosomal aberrations. A variety of genotoxic agents may induce MN formation leading to cell death, genomic instability, or cancer development. In this review, the genetic and epigenetic mechanisms of MN formation after various clastogenic and aneugenic effects on cell division and cell cycle are described. The knowledge accumulated in literature on cytotoxicity of various genotoxins is precisely reflected and individual sensitivity to MN formation due to single gene polymorphisms is discussed. The importance of rapid MN scoring with respect to the cytokinesis-block micronucleus assay is also evaluated.

X Demographics

X Demographics

The data shown below were collected from the profiles of 12 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 526 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Portugal 2 <1%
Germany 1 <1%
Sweden 1 <1%
India 1 <1%
Spain 1 <1%
Japan 1 <1%
United States 1 <1%
Unknown 518 98%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 91 17%
Student > Ph. D. Student 80 15%
Student > Master 74 14%
Researcher 55 10%
Student > Doctoral Student 24 5%
Other 76 14%
Unknown 126 24%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 135 26%
Agricultural and Biological Sciences 95 18%
Medicine and Dentistry 49 9%
Pharmacology, Toxicology and Pharmaceutical Science 23 4%
Environmental Science 22 4%
Other 56 11%
Unknown 146 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 29. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 December 2023.
All research outputs
#1,339,363
of 25,507,011 outputs
Outputs from Frontiers in Genetics
#241
of 13,743 outputs
Outputs of similar age
#11,342
of 289,563 outputs
Outputs of similar age from Frontiers in Genetics
#12
of 318 outputs
Altmetric has tracked 25,507,011 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 13,743 research outputs from this source. They receive a mean Attention Score of 3.8. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 289,563 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 318 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.