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The mysterious case of the C. elegans gut granule: death fluorescence, anthranilic acid and the kynurenine pathway

Overview of attention for article published in Frontiers in Genetics, January 2013
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (76th percentile)
  • Good Attention Score compared to outputs of the same age and source (76th percentile)

Mentioned by

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4 X users
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3 Wikipedia pages

Citations

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46 Dimensions

Readers on

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151 Mendeley
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Title
The mysterious case of the C. elegans gut granule: death fluorescence, anthranilic acid and the kynurenine pathway
Published in
Frontiers in Genetics, January 2013
DOI 10.3389/fgene.2013.00151
Pubmed ID
Authors

Cassandra Coburn, David Gems

Abstract

Gut granules are lysosome-like organelles with acidic interiors that are found in large numbers within the intestine of the nematode Caenorhabditis elegans. They are particularly prominent when viewed under ultraviolet light, which causes them to emit intense blue fluorescence. Yet the function of these large and abundant organelles in this heavily-studied model organism remains unclear. One possibility is that they serve as storage organelles, for example of zinc. A new clue to gut granule function is the identification of the blue fluorescent material that they contain as a glycosylated form of anthranilic acid, which is derived from tryptophan by action of the kynurenine pathway. This compound can also serve a surprising role as a natural, endogenous marker of organismal death.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 151 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 <1%
United States 1 <1%
Unknown 149 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 35 23%
Student > Bachelor 27 18%
Student > Master 22 15%
Researcher 18 12%
Student > Postgraduate 8 5%
Other 16 11%
Unknown 25 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 66 44%
Biochemistry, Genetics and Molecular Biology 28 19%
Medicine and Dentistry 7 5%
Neuroscience 5 3%
Chemistry 5 3%
Other 13 9%
Unknown 27 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 December 2021.
All research outputs
#6,033,029
of 22,769,322 outputs
Outputs from Frontiers in Genetics
#1,714
of 11,758 outputs
Outputs of similar age
#64,293
of 280,939 outputs
Outputs of similar age from Frontiers in Genetics
#74
of 319 outputs
Altmetric has tracked 22,769,322 research outputs across all sources so far. This one has received more attention than most of these and is in the 73rd percentile.
So far Altmetric has tracked 11,758 research outputs from this source. They receive a mean Attention Score of 3.7. This one has done well, scoring higher than 85% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 280,939 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 76% of its contemporaries.
We're also able to compare this research output to 319 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 76% of its contemporaries.