Title |
Meta4: a web application for sharing and annotating metagenomic gene predictions using web services
|
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Published in |
Frontiers in Genetics, January 2013
|
DOI | 10.3389/fgene.2013.00168 |
Pubmed ID | |
Authors |
Emily J. Richardson, Franck Escalettes, Ian Fotheringham, Robert J. Wallace, Mick Watson |
Abstract |
Whole-genome shotgun metagenomics experiments produce DNA sequence data from entire ecosystems, and provide a huge amount of novel information. Gene discovery projects require up-to-date information about sequence homology and domain structure for millions of predicted proteins to be presented in a simple, easy-to-use system. There is a lack of simple, open, flexible tools that allow the rapid sharing of metagenomics datasets with collaborators in a format they can easily interrogate. We present Meta4, a flexible and extensible web application that can be used to share and annotate metagenomic gene predictions. Proteins and predicted domains are stored in a simple relational database, with a dynamic front-end which displays the results in an internet browser. Web services are used to provide up-to-date information about the proteins from homology searches against public databases. Information about Meta4 can be found on the project website, code is available on Github, a cloud image is available, and an example implementation can be seen at. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 6 | 40% |
United States | 2 | 13% |
India | 1 | 7% |
Switzerland | 1 | 7% |
France | 1 | 7% |
Germany | 1 | 7% |
Sweden | 1 | 7% |
Hong Kong | 1 | 7% |
Peru | 1 | 7% |
Other | 0 | 0% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 8 | 53% |
Members of the public | 5 | 33% |
Science communicators (journalists, bloggers, editors) | 2 | 13% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Brazil | 3 | 6% |
Estonia | 2 | 4% |
Sweden | 1 | 2% |
United Kingdom | 1 | 2% |
India | 1 | 2% |
Argentina | 1 | 2% |
United States | 1 | 2% |
Unknown | 39 | 80% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 13 | 27% |
Researcher | 13 | 27% |
Student > Bachelor | 6 | 12% |
Student > Master | 6 | 12% |
Professor | 3 | 6% |
Other | 5 | 10% |
Unknown | 3 | 6% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 23 | 47% |
Biochemistry, Genetics and Molecular Biology | 7 | 14% |
Computer Science | 5 | 10% |
Environmental Science | 2 | 4% |
Engineering | 2 | 4% |
Other | 6 | 12% |
Unknown | 4 | 8% |