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Chromatin structure and transposable elements in organismal aging

Overview of attention for article published in Frontiers in Genetics, January 2013
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  • Above-average Attention Score compared to outputs of the same age and source (64th percentile)

Mentioned by

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2 X users
reddit
1 Redditor

Citations

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116 Dimensions

Readers on

mendeley
223 Mendeley
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1 CiteULike
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Title
Chromatin structure and transposable elements in organismal aging
Published in
Frontiers in Genetics, January 2013
DOI 10.3389/fgene.2013.00274
Pubmed ID
Authors

Jason G Wood, Stephen L Helfand

Abstract

Epigenetic regulatory mechanisms are increasingly appreciated as central to a diverse array of biological processes, including aging. An association between heterochromatic silencing and longevity has long been recognized in yeast, and in more recent years evidence has accumulated of age-related chromatin changes in Caenorhabditis elegans, Drosophila, and mouse model systems, as well as in the tissue culture-based replicative senescence model of cell aging. In addition, a number of studies have linked expression of transposable elements (TEs), as well as changes in the RNAi pathways that cells use to combat TEs, to the aging process. This review summarizes the recent evidence linking chromatin structure and function to aging, with a particular focus on the relationship of heterochromatin structure to organismal aging.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 223 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 4 2%
United Kingdom 3 1%
United States 2 <1%
Brazil 1 <1%
Japan 1 <1%
China 1 <1%
Unknown 211 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 63 28%
Researcher 45 20%
Student > Master 23 10%
Student > Bachelor 22 10%
Student > Doctoral Student 9 4%
Other 30 13%
Unknown 31 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 82 37%
Biochemistry, Genetics and Molecular Biology 64 29%
Neuroscience 9 4%
Medicine and Dentistry 5 2%
Immunology and Microbiology 4 2%
Other 23 10%
Unknown 36 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 December 2013.
All research outputs
#13,173,409
of 23,577,654 outputs
Outputs from Frontiers in Genetics
#2,698
of 12,604 outputs
Outputs of similar age
#155,128
of 284,930 outputs
Outputs of similar age from Frontiers in Genetics
#110
of 318 outputs
Altmetric has tracked 23,577,654 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 12,604 research outputs from this source. They receive a mean Attention Score of 3.7. This one has done well, scoring higher than 77% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 284,930 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 318 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 64% of its contemporaries.