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Circ2Traits: a comprehensive database for circular RNA potentially associated with disease and traits

Overview of attention for article published in Frontiers in Genetics, January 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (86th percentile)
  • High Attention Score compared to outputs of the same age and source (84th percentile)

Mentioned by

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3 X users
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1 patent
wikipedia
1 Wikipedia page
googleplus
1 Google+ user

Citations

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409 Dimensions

Readers on

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198 Mendeley
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Title
Circ2Traits: a comprehensive database for circular RNA potentially associated with disease and traits
Published in
Frontiers in Genetics, January 2013
DOI 10.3389/fgene.2013.00283
Pubmed ID
Authors

Suman Ghosal, Shaoli Das, Rituparno Sen, Piyali Basak, Jayprokas Chakrabarti

Abstract

Circular RNAs are new players in regulation of post transcriptional gene expression. Animal genomes express many circular RNAs from diverse genomic locations. A recent study has validated a fairly large number of circular RNAs in human, mouse, and nematode. Circular RNAs play a crucial role in fine tuning the level of miRNA mediated regulation of gene expression by sequestering the miRNAs. Their interaction with disease associated miRNAs indicates that circular RNAs are important for disease regulation. In this paper we studied the potential association of circular RNAs (circRNA) with human diseases in two different ways. Firstly, the interactions of circRNAs with disease associated miRNAs were identified, following which the likelihood of a circRNA being associated with a disease was calculated. For the miRNAs associated with individual diseases, we constructed a network of predicted interactions between the miRNAs and protein coding, long non-coding and circular RNA genes. We carried out gene ontology (GO) enrichment analysis on the set of protein coding genes in the miRNA- circRNA interactome of individual diseases to check the enrichment of genes associated with particular biological processes. Secondly, disease associated SNPs were mapped on circRNA loci, and Argonaute (Ago) interaction sites on circular RNAs were identified. We compiled a database of disease-circRNA association in Circ2Traits (http://gyanxet-beta.com/circdb/), the first comprehensive knowledgebase of potential association of circular RNAs with diseases in human.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 198 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 1%
Japan 1 <1%
Singapore 1 <1%
Brazil 1 <1%
Unknown 193 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 44 22%
Researcher 36 18%
Student > Master 21 11%
Student > Bachelor 21 11%
Student > Postgraduate 10 5%
Other 27 14%
Unknown 39 20%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 57 29%
Agricultural and Biological Sciences 52 26%
Medicine and Dentistry 18 9%
Computer Science 9 5%
Neuroscience 4 2%
Other 14 7%
Unknown 44 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 May 2017.
All research outputs
#3,677,015
of 22,736,112 outputs
Outputs from Frontiers in Genetics
#1,112
of 11,757 outputs
Outputs of similar age
#38,982
of 280,780 outputs
Outputs of similar age from Frontiers in Genetics
#50
of 319 outputs
Altmetric has tracked 22,736,112 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 11,757 research outputs from this source. They receive a mean Attention Score of 3.7. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 280,780 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 319 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.