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Allergic asthma biomarkers using systems approaches

Overview of attention for article published in Frontiers in Genetics, January 2014
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  • Above-average Attention Score compared to outputs of the same age and source (57th percentile)

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3 X users
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1 Google+ user
reddit
1 Redditor

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57 Mendeley
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Title
Allergic asthma biomarkers using systems approaches
Published in
Frontiers in Genetics, January 2014
DOI 10.3389/fgene.2013.00308
Pubmed ID
Authors

Gaurab Sircar, Bodhisattwa Saha, Swati G. Bhattacharya, Sudipto Saha

Abstract

Asthma is characterized by lung inflammation caused by complex interaction between the immune system and environmental factors such as allergens and inorganic pollutants. Recent research in this field is focused on discovering new biomarkers associated with asthma pathogenesis. This review illustrates updated research associating biomarkers of allergic asthma and their potential use in systems biology of the disease. We focus on biomolecules with altered expression, which may serve as inflammatory, diagnostic and therapeutic biomarkers of asthma discovered in human or experimental asthma model using genomic, proteomic and epigenomic approaches for gene and protein expression profiling. These include high-throughput technologies such as state of the art microarray and proteomics Mass Spectrometry (MS) platforms. Emerging concepts of molecular interactions and pathways may provide new insights in searching potential clinical biomarkers. We summarized certain pathways with significant linkage to asthma pathophysiology by analyzing the compiled biomarkers. Systems approaches with this data can identify the regulating networks, which will eventually identify the key biomarkers to be used for diagnostics and drug discovery.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 57 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Unknown 56 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 12 21%
Researcher 10 18%
Other 5 9%
Professor > Associate Professor 5 9%
Student > Master 5 9%
Other 12 21%
Unknown 8 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 21 37%
Immunology and Microbiology 8 14%
Medicine and Dentistry 8 14%
Biochemistry, Genetics and Molecular Biology 6 11%
Engineering 3 5%
Other 3 5%
Unknown 8 14%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 January 2014.
All research outputs
#12,890,747
of 22,738,543 outputs
Outputs from Frontiers in Genetics
#2,719
of 11,757 outputs
Outputs of similar age
#156,671
of 305,211 outputs
Outputs of similar age from Frontiers in Genetics
#22
of 54 outputs
Altmetric has tracked 22,738,543 research outputs across all sources so far. This one is in the 42nd percentile – i.e., 42% of other outputs scored the same or lower than it.
So far Altmetric has tracked 11,757 research outputs from this source. They receive a mean Attention Score of 3.7. This one has done well, scoring higher than 75% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 305,211 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 54 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 57% of its contemporaries.