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Epigenetic inheritance of cell fates during embryonic development

Overview of attention for article published in Frontiers in Genetics, January 2014
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  • Above-average Attention Score compared to outputs of the same age and source (51st percentile)

Mentioned by

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2 X users
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1 peer review site

Citations

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39 Dimensions

Readers on

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119 Mendeley
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Title
Epigenetic inheritance of cell fates during embryonic development
Published in
Frontiers in Genetics, January 2014
DOI 10.3389/fgene.2014.00019
Pubmed ID
Authors

Sirisha Cheedipudi, Oriana Genolet, Gergana Dobreva

Abstract

During embryonic development a large number of widely differing and specialized cell types with identical genomes are generated from a single totipotent zygote. Tissue specific transcription factors cooperate with epigenetic modifiers to establish cellular identity in differentiated cells and epigenetic regulatory mechanisms contribute to the maintenance of distinct chromatin states and cell-type specific gene expression patterns, a phenomenon referred to as epigenetic memory. This is accomplished via the stable maintenance of various epigenetic marks through successive rounds of cell division. Preservation of DNA methylation patterns is a well-established mechanism of epigenetic memory, but more recently it has become clear that many other epigenetic modifications can also be maintained following DNA replication and cell division. In this review, we present an overview of the current knowledge regarding the role of histone lysine methylation in the establishment and maintenance of stable epigenetic states.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 119 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 <1%
Denmark 1 <1%
France 1 <1%
Brazil 1 <1%
Unknown 115 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 34 29%
Researcher 17 14%
Student > Bachelor 14 12%
Student > Master 14 12%
Student > Doctoral Student 7 6%
Other 14 12%
Unknown 19 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 39 33%
Biochemistry, Genetics and Molecular Biology 33 28%
Medicine and Dentistry 11 9%
Psychology 3 3%
Pharmacology, Toxicology and Pharmaceutical Science 2 2%
Other 7 6%
Unknown 24 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 February 2022.
All research outputs
#13,350,541
of 23,033,713 outputs
Outputs from Frontiers in Genetics
#3,003
of 12,087 outputs
Outputs of similar age
#162,242
of 306,717 outputs
Outputs of similar age from Frontiers in Genetics
#24
of 54 outputs
Altmetric has tracked 23,033,713 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 12,087 research outputs from this source. They receive a mean Attention Score of 3.7. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 306,717 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 54 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 51% of its contemporaries.