Title |
Dietary interactions with the bacterial sensing machinery in the intestine: the plant polyphenol case
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Published in |
Frontiers in Genetics, April 2014
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DOI | 10.3389/fgene.2014.00064 |
Pubmed ID | |
Authors |
Noha Ahmed Nasef, Sunali Mehta, Lynnette R. Ferguson |
Abstract |
There are millions of microbes that live in the human gut. These are important in digestion as well as defense. The host immune system needs to be able to distinguish between the harmless bacteria and pathogens. The initial interaction between bacteria and the host happen through the pattern recognition receptors (PRRs). As these receptors are in direct contact with the external environment, this makes them important candidates for regulation by dietary components and therefore potential targets for therapy. In this review, we introduce some of the main PRRs including a cellular process known as autophagy, and how they function. Additionally we review dietary phytochemicals from plants which are believed to be beneficial for humans. The purpose of this review was to give a better understanding of how these components work in order to create better awareness on how they could be explored in the future. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Switzerland | 1 | 17% |
United States | 1 | 17% |
Unknown | 4 | 67% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 4 | 67% |
Practitioners (doctors, other healthcare professionals) | 1 | 17% |
Scientists | 1 | 17% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
New Zealand | 1 | 1% |
United States | 1 | 1% |
Brazil | 1 | 1% |
Unknown | 66 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 13 | 19% |
Researcher | 11 | 16% |
Student > Ph. D. Student | 10 | 14% |
Professor | 7 | 10% |
Student > Doctoral Student | 6 | 9% |
Other | 13 | 19% |
Unknown | 9 | 13% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 28 | 41% |
Medicine and Dentistry | 10 | 14% |
Biochemistry, Genetics and Molecular Biology | 7 | 10% |
Chemistry | 5 | 7% |
Nursing and Health Professions | 2 | 3% |
Other | 8 | 12% |
Unknown | 9 | 13% |