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Losing the stem-loop structure from metazoan mitochondrial tRNAs and co-evolution of interacting factors

Overview of attention for article published in Frontiers in Genetics, May 2014
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1 peer review site

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Title
Losing the stem-loop structure from metazoan mitochondrial tRNAs and co-evolution of interacting factors
Published in
Frontiers in Genetics, May 2014
DOI 10.3389/fgene.2014.00109
Pubmed ID
Authors

Yoh-ichi Watanabe, Takuma Suematsu, Takashi Ohtsuki

Abstract

Conventional tRNAs have highly conserved sequences, four-armed cloverleaf secondary structures, and L-shaped tertiary structures. However, metazoan mitochondrial tRNAs contain several exceptional structures. Almost all tRNAs(Ser) for AGY/N codons lack the D-arm. Furthermore, in some nematodes, no four-armed cloverleaf-type tRNAs are present: two tRNAs(Ser) without the D-arm and 20 tRNAs without the T-arm are found. Previously, we showed that in nematode mitochondria, an extra elongation factor Tu (EF-Tu) has evolved to support interaction with tRNAs lacking the T-arm, which interact with C-terminal domain 3 in conventional EF-Tu. Recent mitochondrial genome analyses have suggested that in metazoan lineages other than nematodes, tRNAs without the T-arm are present. Furthermore, even more simplified tRNAs are predicted in some lineages. In this review, we discuss mitochondrial tRNAs with divergent structures, as well as protein factors, including EF-Tu, that support the function of truncated metazoan mitochondrial tRNAs.

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The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 72 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
Spain 1 1%
United States 1 1%
Unknown 69 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 18 25%
Researcher 13 18%
Student > Bachelor 11 15%
Student > Master 4 6%
Professor 3 4%
Other 11 15%
Unknown 12 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 28 39%
Biochemistry, Genetics and Molecular Biology 20 28%
Chemistry 5 7%
Immunology and Microbiology 1 1%
Unspecified 1 1%
Other 2 3%
Unknown 15 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 May 2014.
All research outputs
#13,408,116
of 22,754,104 outputs
Outputs from Frontiers in Genetics
#3,242
of 11,758 outputs
Outputs of similar age
#112,254
of 227,852 outputs
Outputs of similar age from Frontiers in Genetics
#63
of 115 outputs
Altmetric has tracked 22,754,104 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 11,758 research outputs from this source. They receive a mean Attention Score of 3.7. This one has gotten more attention than average, scoring higher than 70% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 227,852 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 49th percentile – i.e., 49% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 115 others from the same source and published within six weeks on either side of this one. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.