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Culturing intestinal stem cells: applications for colorectal cancer research

Overview of attention for article published in Frontiers in Genetics, June 2014
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  • Above-average Attention Score compared to outputs of the same age (51st percentile)
  • Average Attention Score compared to outputs of the same age and source

Mentioned by

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3 X users

Citations

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9 Dimensions

Readers on

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87 Mendeley
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Title
Culturing intestinal stem cells: applications for colorectal cancer research
Published in
Frontiers in Genetics, June 2014
DOI 10.3389/fgene.2014.00169
Pubmed ID
Authors

Masayuki Fujii, Toshiro Sato

Abstract

Recent advance of sequencing technology has revealed genetic alterations in colorectal cancer (CRC). The biological function of recurrently mutated genes has been intensively investigated through mouse genetic models and CRC cell lines. Although these experimental models may not fully reflect biological traits of human intestinal epithelium, they provided insights into the understanding of intestinal stem cell self-renewal, leading to the development of novel human intestinal organoid culture system. Intestinal organoid culture enabled to expand normal or tumor epithelial cells in vitro retaining their stem cell self-renewal and multiple differentiation. Gene manipulation of these cultured cells may provide an attractive tool for investigating genetic events involved in colorectal carcinogenesis.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 87 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Iran, Islamic Republic of 1 1%
United States 1 1%
France 1 1%
Unknown 84 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 20 23%
Researcher 20 23%
Student > Bachelor 12 14%
Student > Master 10 11%
Student > Doctoral Student 5 6%
Other 12 14%
Unknown 8 9%
Readers by discipline Count As %
Agricultural and Biological Sciences 29 33%
Biochemistry, Genetics and Molecular Biology 22 25%
Medicine and Dentistry 10 11%
Engineering 3 3%
Immunology and Microbiology 3 3%
Other 9 10%
Unknown 11 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 September 2014.
All research outputs
#13,334,478
of 22,757,090 outputs
Outputs from Frontiers in Genetics
#3,151
of 11,758 outputs
Outputs of similar age
#110,207
of 228,027 outputs
Outputs of similar age from Frontiers in Genetics
#62
of 123 outputs
Altmetric has tracked 22,757,090 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 11,758 research outputs from this source. They receive a mean Attention Score of 3.7. This one has gotten more attention than average, scoring higher than 72% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 228,027 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 51% of its contemporaries.
We're also able to compare this research output to 123 others from the same source and published within six weeks on either side of this one. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.