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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Genetic factors and manganese-induced neurotoxicity
|
|---|---|
| Published in |
Frontiers in Genetics, August 2014
|
| DOI | 10.3389/fgene.2014.00265 |
| Pubmed ID | |
| Authors |
Pan Chen, Nancy Parmalee, Michael Aschner |
| Abstract |
Manganese (Mn), is a trace metal required for normal physiological processes in humans. Mn levels are tightly regulated, as high levels of Mn result in accumulation in the brain and cause a neurological disease known as manganism. Manganism shares many similarities with Parkinson's disease (PD), both at the physiological level and the cellular level. Exposure to high Mn-containing environments increases the risk of developing manganism. Mn is absorbed primarily through the intestine and then released in the blood. Excessive Mn is secreted in the bile and excreted in feces. Mn enters and exits cells through a number of non-specific importers localized on the cell membrane. Mutations in one of the Mn exporters, SLC30A10 (solute carrier family 30, member 10), result in Mn induced toxicity with liver impairments and neurological dysfunction. Four PD genes have been identified in connection to regulation of Mn toxicity, shedding new light on potential links between manganism and PD. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | 50% |
| India | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 92 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 3% |
| Italy | 1 | 1% |
| Unknown | 88 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 27 | 29% |
| Student > Master | 12 | 13% |
| Student > Bachelor | 9 | 10% |
| Other | 8 | 9% |
| Student > Doctoral Student | 5 | 5% |
| Other | 16 | 17% |
| Unknown | 15 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 21 | 23% |
| Medicine and Dentistry | 16 | 17% |
| Biochemistry, Genetics and Molecular Biology | 13 | 14% |
| Pharmacology, Toxicology and Pharmaceutical Science | 7 | 8% |
| Neuroscience | 5 | 5% |
| Other | 8 | 9% |
| Unknown | 22 | 24% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 August 2014.
All research outputs
#13,917,593
of 22,759,618 outputs
Outputs from Frontiers in Genetics
#3,506
of 11,758 outputs
Outputs of similar age
#115,319
of 229,899 outputs
Outputs of similar age from Frontiers in Genetics
#75
of 133 outputs
Altmetric has tracked 22,759,618 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 11,758 research outputs from this source. They receive a mean Attention Score of 3.7. This one has gotten more attention than average, scoring higher than 67% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 229,899 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 133 others from the same source and published within six weeks on either side of this one. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.