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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Insights into the epigenomic landscape of the human malaria vector Anopheles gambiae
|
|---|---|
| Published in |
Frontiers in Genetics, August 2014
|
| DOI | 10.3389/fgene.2014.00277 |
| Pubmed ID | |
| Authors |
Elena Gómez-Díaz, Ana Rivero, Fabrice Chandre, Victor G. Corces |
| Abstract |
The epigenome of the human malaria vector Anopheles gambiae was characterized in midgut cells by mapping the distribution and levels of two post-translational histone modifications, H3K27ac and H3K27me3. These histone profiles were then correlated with levels of gene expression obtained by RNA-seq. Analysis of the transcriptome of A. gambiae midguts and salivary glands led to the discovery of 13,898 new transcripts not present in the most recent genome assembly. A subset of these transcripts is differentially expressed between midgut and salivary glands. The enrichment profiles of H3K27ac and H3K27me3 are mutually exclusive and associate with high and low levels of transcription, respectively. This distribution agrees with previous findings in Drosophila showing association of these two histone modifications with either active or inactive transcriptional states, including Polycomb-associated domains in silenced genes. This study provides a mosquito epigenomics platform for future comparative studies in other mosquito species, opening future investigations into the role of epigenetic processes in vector-borne systems of medical and economic importance. |
X Demographics
The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 2 | 29% |
| France | 1 | 14% |
| Spain | 1 | 14% |
| Unknown | 3 | 43% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 6 | 86% |
| Scientists | 1 | 14% |
Mendeley readers
The data shown below were compiled from readership statistics for 78 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 1% |
| South Africa | 1 | 1% |
| Unknown | 76 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 19 | 24% |
| Student > Ph. D. Student | 18 | 23% |
| Student > Master | 6 | 8% |
| Student > Bachelor | 5 | 6% |
| Student > Doctoral Student | 5 | 6% |
| Other | 12 | 15% |
| Unknown | 13 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 27 | 35% |
| Biochemistry, Genetics and Molecular Biology | 23 | 29% |
| Immunology and Microbiology | 5 | 6% |
| Medicine and Dentistry | 3 | 4% |
| Sports and Recreations | 1 | 1% |
| Other | 1 | 1% |
| Unknown | 18 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 September 2014.
All research outputs
#7,061,613
of 23,577,654 outputs
Outputs from Frontiers in Genetics
#2,145
of 12,604 outputs
Outputs of similar age
#66,057
of 232,234 outputs
Outputs of similar age from Frontiers in Genetics
#44
of 138 outputs
Altmetric has tracked 23,577,654 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 12,604 research outputs from this source. They receive a mean Attention Score of 3.7. This one has done well, scoring higher than 82% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 232,234 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 138 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.