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Sperm epigenomics: challenges and opportunities

Overview of attention for article published in Frontiers in Genetics, September 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (81st percentile)
  • High Attention Score compared to outputs of the same age and source (88th percentile)

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11 X users
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1 Facebook page

Citations

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73 Dimensions

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141 Mendeley
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4 CiteULike
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Title
Sperm epigenomics: challenges and opportunities
Published in
Frontiers in Genetics, September 2014
DOI 10.3389/fgene.2014.00330
Pubmed ID
Authors

Eduard Casas, Tanya Vavouri

Abstract

Sperm is a highly differentiated cell type whose function is to deliver a haploid genome to the oocyte. The sperm "epigenomes" were traditionally considered to be insignificant - the sperm is transcriptionally inactive, its genome is packaged in sperm-specific protamine toroids instead of nucleosomes, and its DNA methylation profile is erased immediately post-fertilization. Yet, in recent years there has been an increase in the number of reported cases of apparent epigenetic inheritance through the male germline, suggesting that the sperm epigenome may transmit information between generations. At the same time, technical advances have made the genome-wide profiling of different layers of the sperm epigenome feasible. As a result, a large number of datasets have been recently generated and analyzed with the aim to better understand what non-genetic material is contained within the sperm and whether it has any function post-fertilization. Here, we provide an overview of the current knowledge of the sperm epigenomes as well as the challenges in analysing them and the opportunities in understanding the potential non-genetic carriers of information in sperm.

X Demographics

X Demographics

The data shown below were collected from the profiles of 11 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 141 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 <1%
Switzerland 1 <1%
France 1 <1%
Norway 1 <1%
Korea, Republic of 1 <1%
Brazil 1 <1%
India 1 <1%
Mexico 1 <1%
Spain 1 <1%
Other 0 0%
Unknown 132 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 29 21%
Researcher 26 18%
Student > Master 19 13%
Student > Bachelor 12 9%
Professor 11 8%
Other 22 16%
Unknown 22 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 44 31%
Biochemistry, Genetics and Molecular Biology 32 23%
Neuroscience 16 11%
Medicine and Dentistry 13 9%
Pharmacology, Toxicology and Pharmaceutical Science 2 1%
Other 6 4%
Unknown 28 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 November 2023.
All research outputs
#4,635,307
of 25,349,035 outputs
Outputs from Frontiers in Genetics
#1,434
of 13,631 outputs
Outputs of similar age
#46,086
of 256,944 outputs
Outputs of similar age from Frontiers in Genetics
#15
of 118 outputs
Altmetric has tracked 25,349,035 research outputs across all sources so far. Compared to these this one has done well and is in the 81st percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 13,631 research outputs from this source. They receive a mean Attention Score of 3.8. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 256,944 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 81% of its contemporaries.
We're also able to compare this research output to 118 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.