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Mendeley readers
Attention Score in Context
| Title |
The role of non-coding RNAs in the regulation of stem cells and progenitors in the normal mammary gland and in breast tumors
|
|---|---|
| Published in |
Frontiers in Genetics, February 2015
|
| DOI | 10.3389/fgene.2015.00072 |
| Pubmed ID | |
| Authors |
Chiara Tordonato, Pier Paolo Di Fiore, Francesco Nicassio |
| Abstract |
The outlook on stem cell (SC) biology is shifting from a rigid hierarchical to a more flexible model in which the identity and the behavior of adult SCs, far from being fixed, are determined by the dynamic integration of cell autonomous and non-autonomous mechanisms. Within this framework, the recent discovery of thousands of non-coding RNAs (ncRNAs) with regulatory function is redefining the landscape of transcriptome regulation, highlighting the interplay of epigenetic, transcriptional, and post-transcriptional mechanisms in the specification of cell fate and in the regulation of developmental processes. Furthermore, the expression of ncRNAs is often tissue- or even cell type-specific, emphasizing their involvement in defining space, time and developmental stages in gene regulation. Such a role of ncRNAs has been investigated in embryonic and induced pluripotent SCs, and in numerous types of adult SCs and progenitors, including those of the breast, which will be the topic of this review. We will focus on ncRNAs with an important role in breast cancer, in particular in mammary cancer SCs and progenitors, and highlight the ncRNA-based circuitries whose subversion alters a number of the epigenetic, transcriptional, and post-transcriptional events that control "stemness" in the physiological setting. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 20% |
| France | 1 | 20% |
| Switzerland | 1 | 20% |
| Unknown | 2 | 40% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 80% |
| Scientists | 1 | 20% |
Mendeley readers
The data shown below were compiled from readership statistics for 85 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Finland | 1 | 1% |
| China | 1 | 1% |
| Unknown | 83 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 19 | 22% |
| Researcher | 16 | 19% |
| Student > Master | 12 | 14% |
| Student > Bachelor | 6 | 7% |
| Student > Doctoral Student | 4 | 5% |
| Other | 7 | 8% |
| Unknown | 21 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 27 | 32% |
| Agricultural and Biological Sciences | 23 | 27% |
| Medicine and Dentistry | 5 | 6% |
| Materials Science | 2 | 2% |
| Nursing and Health Professions | 1 | 1% |
| Other | 6 | 7% |
| Unknown | 21 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 April 2015.
All research outputs
#12,625,884
of 22,793,427 outputs
Outputs from Frontiers in Genetics
#2,527
of 11,761 outputs
Outputs of similar age
#111,927
of 255,577 outputs
Outputs of similar age from Frontiers in Genetics
#69
of 153 outputs
Altmetric has tracked 22,793,427 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 11,761 research outputs from this source. They receive a mean Attention Score of 3.7. This one has done well, scoring higher than 78% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 255,577 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 55% of its contemporaries.
We're also able to compare this research output to 153 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 54% of its contemporaries.