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X Demographics
Mendeley readers
Attention Score in Context
| Title |
On the road with WRAP53β: guardian of Cajal bodies and genome integrity
|
|---|---|
| Published in |
Frontiers in Genetics, March 2015
|
| DOI | 10.3389/fgene.2015.00091 |
| Pubmed ID | |
| Authors |
Sofia Henriksson, Marianne Farnebo |
| Abstract |
The WRAP53 gene encodes both an antisense transcript (WRAP53α) that stabilizes the tumor suppressor p53 and a protein (WRAP53β) involved in maintenance of Cajal bodies, telomere elongation and DNA repair. WRAP53β is one of many proteins containing WD40 domains, known to mediate a variety of cellular processes. These proteins lack enzymatic activity, acting instead as platforms for the assembly of large complexes of proteins and RNAs thus facilitating their interactions. WRAP53β mediates site-specific interactions between Cajal body factors and DNA repair proteins. Moreover, dysfunction of this protein has been linked to premature aging, cancer and neurodegeneration. Here we summarize the current state of knowledge concerning the multifaceted roles of WRAP53β in intracellular trafficking, formation of the Cajal body, DNA repair and maintenance of genomic integrity and discuss potential crosstalk between these processes. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 53 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 1 | 2% |
| Unknown | 52 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 15 | 28% |
| Student > Ph. D. Student | 10 | 19% |
| Student > Master | 7 | 13% |
| Student > Bachelor | 6 | 11% |
| Student > Doctoral Student | 2 | 4% |
| Other | 4 | 8% |
| Unknown | 9 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 16 | 30% |
| Agricultural and Biological Sciences | 12 | 23% |
| Medicine and Dentistry | 6 | 11% |
| Neuroscience | 4 | 8% |
| Chemistry | 2 | 4% |
| Other | 4 | 8% |
| Unknown | 9 | 17% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 July 2015.
All research outputs
#7,212,132
of 22,796,179 outputs
Outputs from Frontiers in Genetics
#2,282
of 11,761 outputs
Outputs of similar age
#85,869
of 263,362 outputs
Outputs of similar age from Frontiers in Genetics
#62
of 148 outputs
Altmetric has tracked 22,796,179 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 11,761 research outputs from this source. They receive a mean Attention Score of 3.7. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 263,362 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.
We're also able to compare this research output to 148 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 55% of its contemporaries.