You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
X Demographics
Mendeley readers
Attention Score in Context
| Title |
Clinical applications of next generation sequencing in cancer: from panels, to exomes, to genomes
|
|---|---|
| Published in |
Frontiers in Genetics, June 2015
|
| DOI | 10.3389/fgene.2015.00215 |
| Pubmed ID | |
| Authors |
Tony Shen, Stefan Hans Pajaro-Van de Stadt, Nai Chien Yeat, Jimmy C.-H. Lin |
| Abstract |
This article will review recent impact of massively parallel next-generation sequencing (NGS) in our understanding and treatment of cancer. While whole exome sequencing (WES) remains popular and effective as a method of genetically profiling different cancers, advances in sequencing technology has enabled an increasing number of whole-genome based studies. Clinically, NGS has been used or is being developed for genetic screening, diagnostics, and clinical assessment. Though challenges remain, clinicians are in the early stages of using genetic data to make treatment decisions for cancer patients. As the integration of NGS in the study and treatment of cancer continues to mature, we believe that the field of cancer genomics will need to move toward more complete 100% genome sequencing. Current technologies and methods are largely limited to coding regions of the genome. A number of recent studies have demonstrated that mutations in non-coding regions may have direct tumorigenic effects or lead to genetic instability. Non-coding regions represent an important frontier in cancer genomics. |
X Demographics
The data shown below were collected from the profiles of 13 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| India | 2 | 15% |
| United Kingdom | 2 | 15% |
| Spain | 1 | 8% |
| Israel | 1 | 8% |
| Ireland | 1 | 8% |
| United States | 1 | 8% |
| Switzerland | 1 | 8% |
| Unknown | 4 | 31% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 8 | 62% |
| Scientists | 5 | 38% |
Mendeley readers
The data shown below were compiled from readership statistics for 219 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | <1% |
| United Kingdom | 1 | <1% |
| Unknown | 216 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 40 | 18% |
| Student > Master | 30 | 14% |
| Other | 28 | 13% |
| Student > Ph. D. Student | 25 | 11% |
| Student > Bachelor | 19 | 9% |
| Other | 37 | 17% |
| Unknown | 40 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 50 | 23% |
| Agricultural and Biological Sciences | 50 | 23% |
| Medicine and Dentistry | 47 | 21% |
| Computer Science | 5 | 2% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 2% |
| Other | 16 | 7% |
| Unknown | 47 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 October 2023.
All research outputs
#3,482,229
of 25,734,859 outputs
Outputs from Frontiers in Genetics
#986
of 13,784 outputs
Outputs of similar age
#41,980
of 278,421 outputs
Outputs of similar age from Frontiers in Genetics
#12
of 86 outputs
Altmetric has tracked 25,734,859 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 13,784 research outputs from this source. They receive a mean Attention Score of 3.8. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 278,421 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 86 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 86% of its contemporaries.