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Simultaneous inference of haplotypes and alleles at a causal gene

Overview of attention for article published in Frontiers in Genetics, October 2015
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Title
Simultaneous inference of haplotypes and alleles at a causal gene
Published in
Frontiers in Genetics, October 2015
DOI 10.3389/fgene.2015.00291
Pubmed ID
Authors

Fabrice Larribe, Mathieu J. Dupont, Gabrielle Boucher

Abstract

We present a methodology which jointly infers haplotypes and the causal alleles at a gene influencing a given trait. Often in human genetic studies, the available data consists of genotypes (series of genetic markers along the chromosomes) and a phenotype. However, for many genetic analyses, one needs haplotypes instead of genotypes. Our methodology is not only able to estimate haplotypes conditionally on the disease status, but is also able to infer the alleles at the unknown disease locus. Some applications of our methodology are in genetic mapping and in genetic counseling.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 10 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Italy 1 10%
Unknown 9 90%

Demographic breakdown

Readers by professional status Count As %
Student > Master 3 30%
Professor 2 20%
Student > Postgraduate 2 20%
Researcher 2 20%
Student > Ph. D. Student 1 10%
Other 0 0%
Readers by discipline Count As %
Agricultural and Biological Sciences 6 60%
Mathematics 2 20%
Biochemistry, Genetics and Molecular Biology 1 10%
Engineering 1 10%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 October 2015.
All research outputs
#18,428,159
of 22,829,683 outputs
Outputs from Frontiers in Genetics
#7,047
of 11,822 outputs
Outputs of similar age
#199,992
of 277,991 outputs
Outputs of similar age from Frontiers in Genetics
#53
of 63 outputs
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So far Altmetric has tracked 11,822 research outputs from this source. They receive a mean Attention Score of 3.7. This one is in the 27th percentile – i.e., 27% of its peers scored the same or lower than it.
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We're also able to compare this research output to 63 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.