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The Impact of KIR Polymorphism on the Risk of Developing Cancer: Not as Strong as Imagined?

Overview of attention for article published in Frontiers in Genetics, June 2016
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Title
The Impact of KIR Polymorphism on the Risk of Developing Cancer: Not as Strong as Imagined?
Published in
Frontiers in Genetics, June 2016
DOI 10.3389/fgene.2016.00121
Pubmed ID
Authors

Danillo G. Augusto

Abstract

The polymorphism of killer cell immunoglobulin-like receptors (KIR) has been associated with several diseases, including infection, autoimmunity and cancer. KIR molecules are a family of receptors expressed on the surface of natural killer cells (NK), frontline defense of innate immunity against microorganisms and neoplastic cells. Some studies have shown conflicting results concerning the role that KIR polymorphism plays in tumor susceptibility, particularly in leukemia and lymphoma. Interestingly, the presence of HLA ligands is sometimes strongly associated with several types of cancer and apparently is not related with their interaction with KIR. This manuscript briefly reviews the uncommon polymorphism of KIR and critically summarizes the recent findings with regards of the importance of KIR variation for cancer susceptibility.

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The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 52 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 52 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 12 23%
Student > Master 11 21%
Student > Ph. D. Student 9 17%
Student > Doctoral Student 5 10%
Student > Bachelor 2 4%
Other 2 4%
Unknown 11 21%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 14 27%
Immunology and Microbiology 11 21%
Agricultural and Biological Sciences 9 17%
Medicine and Dentistry 5 10%
Nursing and Health Professions 2 4%
Other 1 2%
Unknown 10 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 July 2016.
All research outputs
#15,379,002
of 22,879,161 outputs
Outputs from Frontiers in Genetics
#5,459
of 11,919 outputs
Outputs of similar age
#222,707
of 351,565 outputs
Outputs of similar age from Frontiers in Genetics
#36
of 54 outputs
Altmetric has tracked 22,879,161 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 11,919 research outputs from this source. They receive a mean Attention Score of 3.7. This one is in the 48th percentile – i.e., 48% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 351,565 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 54 others from the same source and published within six weeks on either side of this one. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.