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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Better Living through Chemistry: Caloric Restriction (CR) and CR Mimetics Alter Genome Function to Promote Increased Health and Lifespan
|
|---|---|
| Published in |
Frontiers in Genetics, August 2016
|
| DOI | 10.3389/fgene.2016.00142 |
| Pubmed ID | |
| Authors |
Zoe E. Gillespie, Joshua Pickering, Christopher H. Eskiw |
| Abstract |
Caloric restriction (CR), defined as decreased nutrient intake without causing malnutrition, has been documented to increase both health and lifespan across numerous organisms, including humans. Many drugs and other compounds naturally occurring in our diet (nutraceuticals) have been postulated to act as mimetics of caloric restriction, leading to a wave of research investigating the efficacy of these compounds in preventing age-related diseases and promoting healthier, longer lifespans. Although well studied at the biochemical level, there are still many unanswered questions about how CR and CR mimetics impact genome function and structure. Here we discuss how genome function and structure are influenced by CR and potential CR mimetics, including changes in gene expression profiles and epigenetic modifications and their potential to identify the genetic fountain of youth. |
X Demographics
The data shown below were collected from the profiles of 10 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | 40% |
| Italy | 1 | 10% |
| Estonia | 1 | 10% |
| United Kingdom | 1 | 10% |
| France | 1 | 10% |
| Switzerland | 1 | 10% |
| Unknown | 1 | 10% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 7 | 70% |
| Practitioners (doctors, other healthcare professionals) | 2 | 20% |
| Scientists | 1 | 10% |
Mendeley readers
The data shown below were compiled from readership statistics for 129 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Iran, Islamic Republic of | 1 | <1% |
| Germany | 1 | <1% |
| Korea, Republic of | 1 | <1% |
| Unknown | 126 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 21 | 16% |
| Researcher | 18 | 14% |
| Student > Master | 16 | 12% |
| Student > Bachelor | 14 | 11% |
| Professor | 7 | 5% |
| Other | 18 | 14% |
| Unknown | 35 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 33 | 26% |
| Medicine and Dentistry | 14 | 11% |
| Agricultural and Biological Sciences | 14 | 11% |
| Pharmacology, Toxicology and Pharmaceutical Science | 9 | 7% |
| Neuroscience | 7 | 5% |
| Other | 12 | 9% |
| Unknown | 40 | 31% |
Attention Score in Context
This research output has an Altmetric Attention Score of 18. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 September 2017.
All research outputs
#1,782,360
of 22,883,326 outputs
Outputs from Frontiers in Genetics
#395
of 11,919 outputs
Outputs of similar age
#33,784
of 343,111 outputs
Outputs of similar age from Frontiers in Genetics
#5
of 50 outputs
Altmetric has tracked 22,883,326 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 11,919 research outputs from this source. They receive a mean Attention Score of 3.7. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 343,111 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 50 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.