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Ubiquitination and SUMOylation in Telomere Maintenance and Dysfunction

Overview of attention for article published in Frontiers in Genetics, May 2017
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Title
Ubiquitination and SUMOylation in Telomere Maintenance and Dysfunction
Published in
Frontiers in Genetics, May 2017
DOI 10.3389/fgene.2017.00067
Pubmed ID
Authors

Zeliha Yalçin, Carolin Selenz, Jacqueline J L Jacobs

Abstract

Telomeres are essential nucleoprotein structures at linear chromosomes that maintain genome integrity by protecting chromosome ends from being recognized and processed as damaged DNA. In addition, they limit the cell's proliferative capacity, as progressive loss of telomeric DNA during successive rounds of cell division eventually causes a state of telomere dysfunction that prevents further cell division. When telomeres become critically short, the cell elicits a DNA damage response resulting in senescence, apoptosis or genomic instability, thereby impacting on aging and tumorigenesis. Over the past years substantial progress has been made in understanding the role of post-translational modifications in telomere-related processes, including telomere maintenance, replication and dysfunction. This review will focus on recent findings that establish an essential role for ubiquitination and SUMOylation at telomeres.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 55 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 55 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 13 24%
Student > Master 12 22%
Researcher 12 22%
Student > Doctoral Student 2 4%
Professor 1 2%
Other 3 5%
Unknown 12 22%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 24 44%
Agricultural and Biological Sciences 11 20%
Medicine and Dentistry 3 5%
Chemistry 2 4%
Immunology and Microbiology 1 2%
Other 1 2%
Unknown 13 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 June 2017.
All research outputs
#18,548,834
of 22,973,051 outputs
Outputs from Frontiers in Genetics
#7,102
of 12,010 outputs
Outputs of similar age
#238,962
of 313,690 outputs
Outputs of similar age from Frontiers in Genetics
#46
of 56 outputs
Altmetric has tracked 22,973,051 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 12,010 research outputs from this source. They receive a mean Attention Score of 3.7. This one is in the 27th percentile – i.e., 27% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 313,690 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 56 others from the same source and published within six weeks on either side of this one. This one is in the 3rd percentile – i.e., 3% of its contemporaries scored the same or lower than it.