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Mitochondria: A Common Target for Genetic Mutations and Environmental Toxicants in Parkinson’s Disease

Overview of attention for article published in Frontiers in Genetics, November 2017
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  • Good Attention Score compared to outputs of the same age (72nd percentile)
  • Good Attention Score compared to outputs of the same age and source (69th percentile)

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Title
Mitochondria: A Common Target for Genetic Mutations and Environmental Toxicants in Parkinson’s Disease
Published in
Frontiers in Genetics, November 2017
DOI 10.3389/fgene.2017.00177
Pubmed ID
Authors

Martin P. Helley, Jennifer Pinnell, Carolina Sportelli, Kim Tieu

Abstract

Parkinson's disease (PD) is a devastating neurological movement disorder. Since its first discovery 200 years ago, genetic and environmental factors have been identified to play a role in PD development and progression. Although genetic studies have been the predominant driving force in PD research over the last few decades, currently only a small fraction of PD cases can be directly linked to monogenic mutations. The remaining cases have been attributed to other risk associated genes, environmental exposures and gene-environment interactions, making PD a multifactorial disorder with a complex etiology. However, enormous efforts from global research have yielded significant insights into pathogenic mechanisms and potential therapeutic targets for PD. This review will highlight mitochondrial dysfunction as a common pathway involved in both genetic mutations and environmental toxicants linked to PD.

X Demographics

X Demographics

The data shown below were collected from the profiles of 9 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 95 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 95 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 18 19%
Student > Master 17 18%
Student > Ph. D. Student 14 15%
Researcher 8 8%
Student > Doctoral Student 5 5%
Other 11 12%
Unknown 22 23%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 24 25%
Neuroscience 13 14%
Medicine and Dentistry 8 8%
Agricultural and Biological Sciences 7 7%
Environmental Science 3 3%
Other 15 16%
Unknown 25 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 December 2017.
All research outputs
#6,168,445
of 23,008,860 outputs
Outputs from Frontiers in Genetics
#1,794
of 12,067 outputs
Outputs of similar age
#118,216
of 431,641 outputs
Outputs of similar age from Frontiers in Genetics
#25
of 85 outputs
Altmetric has tracked 23,008,860 research outputs across all sources so far. This one has received more attention than most of these and is in the 73rd percentile.
So far Altmetric has tracked 12,067 research outputs from this source. They receive a mean Attention Score of 3.7. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 431,641 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.
We're also able to compare this research output to 85 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.