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The Cellular and Molecular Mechanisms of Immuno-Suppression by Human Type 1 Regulatory T Cells

Overview of attention for article published in Frontiers in immunology, January 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (88th percentile)
  • High Attention Score compared to outputs of the same age and source (93rd percentile)

Mentioned by

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1 X user
patent
3 patents
wikipedia
2 Wikipedia pages

Citations

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139 Dimensions

Readers on

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220 Mendeley
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Title
The Cellular and Molecular Mechanisms of Immuno-Suppression by Human Type 1 Regulatory T Cells
Published in
Frontiers in immunology, January 2012
DOI 10.3389/fimmu.2012.00030
Pubmed ID
Authors

Silvia Gregori, Kevin S. Goudy, Maria Grazia Roncarolo

Abstract

The immuno-regulatory mechanisms of IL-10-producing type 1 regulatory T (Tr1) cells have been widely studied over the years. However, several recent discoveries have shed new light on the cellular and molecular mechanisms that human Tr1 cells use to control immune responses and induce tolerance. In this review we outline the well known and newly discovered regulatory properties of human Tr1 cells and provide an in-depth comparison of the known suppressor mechanisms of Tr1 cells with FOXP3(+) T(reg). We also highlight the role that Tr1 cells play in promoting and maintaining tolerance in autoimmunity, allergy, and transplantation.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 220 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
France 2 <1%
United Kingdom 2 <1%
Brazil 2 <1%
Germany 1 <1%
Canada 1 <1%
Mexico 1 <1%
Unknown 211 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 47 21%
Researcher 40 18%
Student > Master 33 15%
Student > Doctoral Student 23 10%
Student > Bachelor 17 8%
Other 33 15%
Unknown 27 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 61 28%
Immunology and Microbiology 50 23%
Medicine and Dentistry 39 18%
Biochemistry, Genetics and Molecular Biology 17 8%
Engineering 3 1%
Other 15 7%
Unknown 35 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 September 2021.
All research outputs
#3,621,892
of 25,373,627 outputs
Outputs from Frontiers in immunology
#4,011
of 31,516 outputs
Outputs of similar age
#27,620
of 250,101 outputs
Outputs of similar age from Frontiers in immunology
#18
of 275 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 31,516 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 250,101 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 275 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 93% of its contemporaries.