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The Commensal Microbiota Drives Immune Homeostasis

Overview of attention for article published in Frontiers in immunology, January 2012
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Title
The Commensal Microbiota Drives Immune Homeostasis
Published in
Frontiers in immunology, January 2012
DOI 10.3389/fimmu.2012.00033
Pubmed ID
Authors

Marie-Claire Arrieta, Barton Brett Finlay

Abstract

For millions of years, microbes have coexisted with eukaryotic cells at the mucosal surfaces of vertebrates in a complex, yet usually harmonious symbiosis. An ever-expanding number of reports describe how eliminating or shifting the intestinal microbiota has profound effects on the development and functionality of the mucosal and systemic immune systems. Here, we examine some of the mechanisms by which bacterial signals affect immune homeostasis. Focusing on the strategies that microbes use to keep our immune system healthy, as opposed to trying to correct the immune imbalances caused by dysbiosis, may prove to be a more astute and efficient way of treating immune-mediated disease.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 171 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 1%
United States 1 <1%
Portugal 1 <1%
France 1 <1%
Unknown 166 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 37 22%
Student > Ph. D. Student 32 19%
Student > Master 27 16%
Student > Bachelor 20 12%
Student > Doctoral Student 13 8%
Other 21 12%
Unknown 21 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 65 38%
Immunology and Microbiology 24 14%
Biochemistry, Genetics and Molecular Biology 20 12%
Medicine and Dentistry 19 11%
Environmental Science 4 2%
Other 16 9%
Unknown 23 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 November 2013.
All research outputs
#22,756,649
of 25,371,288 outputs
Outputs from Frontiers in immunology
#27,412
of 31,507 outputs
Outputs of similar age
#228,471
of 250,083 outputs
Outputs of similar age from Frontiers in immunology
#161
of 275 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 31,507 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 250,083 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 275 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.