Title |
Controlling the HIV/AIDS epidemic: current status and global challenges
|
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Published in |
Frontiers in immunology, January 2012
|
DOI | 10.3389/fimmu.2012.00250 |
Pubmed ID | |
Authors |
Thorsten Demberg, Marjorie Robert-Guroff |
Abstract |
This review provides an overview of the current status of the global HIV pandemic and strategies to bring it under control. It updates numerous preventive approaches including behavioral interventions, male circumcision (MC), pre- and post-exposure prophylaxis (PREP and PEP), vaccines, and microbicides. The manuscript summarizes current anti-retroviral treatment options, their impact in the western world, and difficulties faced by emerging and resource-limited nations in providing and maintaining appropriate treatment regimens. Current clinical and pre-clinical approaches toward a cure for HIV are described, including new drug compounds that target viral reservoirs and gene therapy approaches aimed at altering susceptibility to HIV infection. Recent progress in vaccine development is summarized, including novel approaches and new discoveries. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 50% |
Switzerland | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
South Africa | 2 | 3% |
Slovenia | 1 | 1% |
Colombia | 1 | 1% |
Unknown | 74 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 15 | 19% |
Researcher | 12 | 15% |
Student > Ph. D. Student | 9 | 12% |
Student > Bachelor | 7 | 9% |
Student > Postgraduate | 6 | 8% |
Other | 13 | 17% |
Unknown | 16 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 17 | 22% |
Biochemistry, Genetics and Molecular Biology | 10 | 13% |
Medicine and Dentistry | 9 | 12% |
Nursing and Health Professions | 8 | 10% |
Social Sciences | 6 | 8% |
Other | 10 | 13% |
Unknown | 18 | 23% |