Title |
Toward a molecular understanding of adaptive immunity: a chronology, part I
|
---|---|
Published in |
Frontiers in immunology, January 2012
|
DOI | 10.3389/fimmu.2012.00369 |
Pubmed ID | |
Authors |
Kendall A. Smith |
Abstract |
The adaptive immune system has been the core of immunology for the past century, as immunologists have been primarily focused on understanding the basis for adaptive immunity for the better part of this time. Immunological thought has undergone an evolution with regard to our understanding as the complexity of the cells and the molecules of the system became elucidated. The original immunologists performed their experiments with whole animals (or humans), and for the most part they were focused on observing what happens when a foreign substance is introduced into the body. However, since Burnet formulated his clonal selection theory we have witnessed reductionist science focused first on cell populations, then individual cells and finally on molecules, in our quests to learn how the system works. This review is the first part of a chronology of our evolution toward a molecular understanding of adaptive immunity. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Switzerland | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United Kingdom | 1 | 1% |
United States | 1 | 1% |
France | 1 | 1% |
Unknown | 66 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 13 | 19% |
Researcher | 13 | 19% |
Student > Bachelor | 11 | 16% |
Student > Doctoral Student | 4 | 6% |
Student > Master | 4 | 6% |
Other | 9 | 13% |
Unknown | 15 | 22% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 21 | 30% |
Immunology and Microbiology | 12 | 17% |
Biochemistry, Genetics and Molecular Biology | 8 | 12% |
Medicine and Dentistry | 8 | 12% |
Nursing and Health Professions | 1 | 1% |
Other | 4 | 6% |
Unknown | 15 | 22% |