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Role of inositol phospholipid signaling in natural killer cell biology

Overview of attention for article published in Frontiers in immunology, January 2013
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Title
Role of inositol phospholipid signaling in natural killer cell biology
Published in
Frontiers in immunology, January 2013
DOI 10.3389/fimmu.2013.00047
Pubmed ID
Authors

Matthew Gumbleton, William G. Kerr

Abstract

Natural killer (NK) cells are important for host defense against malignancy and infection. At a cellular level NK cells are activated when signals from activating receptors exceed signaling from inhibitory receptors. At a molecular level NK cells undergo an education process to both prevent autoimmunity and acquire lytic capacity. Mouse models have shown important roles for inositol phospholipid signaling in lymphocytes. NK cells from mice with deletion in different members of the inositol phospholipid signaling pathway exhibit defects in development, NK cell repertoire expression and effector function. Here we review the current state of knowledge concerning the function of inositol phospholipid signaling components in NK cell biology.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 35 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 35 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 7 20%
Student > Ph. D. Student 7 20%
Student > Bachelor 6 17%
Lecturer 2 6%
Student > Master 2 6%
Other 5 14%
Unknown 6 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 14 40%
Medicine and Dentistry 5 14%
Immunology and Microbiology 3 9%
Biochemistry, Genetics and Molecular Biology 2 6%
Chemistry 2 6%
Other 2 6%
Unknown 7 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 March 2013.
All research outputs
#22,759,802
of 25,374,917 outputs
Outputs from Frontiers in immunology
#27,421
of 31,520 outputs
Outputs of similar age
#258,420
of 289,004 outputs
Outputs of similar age from Frontiers in immunology
#335
of 503 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 31,520 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 289,004 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 503 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.