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Variation between Populations in the Innate Immune Response to Vaccine Adjuvants

Overview of attention for article published in Frontiers in immunology, January 2013
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86 Mendeley
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Title
Variation between Populations in the Innate Immune Response to Vaccine Adjuvants
Published in
Frontiers in immunology, January 2013
DOI 10.3389/fimmu.2013.00081
Pubmed ID
Authors

Tobias R. Kollmann

Abstract

The success of the World Health Organization recommended "Expanded Program of Immunization" (EPI) and similar regional or national programs has been astounding. However, infectious threats currently not covered by these programs continue to infect millions of infants around the world. Furthermore, many infants do not receive existing vaccines either on time or for the required number of doses to provide optimal protection. Nor do all infants around the world develop the same protective immune response to the same vaccine. As a result approximately three million infants die every year from vaccine preventable infections. To tackle these issues, new vaccines need to be developed as well as existing ones made easier to administer. This requires identification of age-optimized vaccine schedules and formulations. In order to be most effective this approach will need to take population-based differences in response to vaccines and adjuvants into account. This review summarizes what is currently known about differences between populations around the world in the innate immune response to existing as well as new and promising vaccine adjuvants.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 86 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 1%
Unknown 85 99%

Demographic breakdown

Readers by professional status Count As %
Researcher 19 22%
Student > Master 12 14%
Student > Bachelor 12 14%
Student > Ph. D. Student 10 12%
Student > Doctoral Student 3 3%
Other 12 14%
Unknown 18 21%
Readers by discipline Count As %
Agricultural and Biological Sciences 25 29%
Medicine and Dentistry 14 16%
Immunology and Microbiology 9 10%
Biochemistry, Genetics and Molecular Biology 7 8%
Social Sciences 3 3%
Other 8 9%
Unknown 20 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 December 2020.
All research outputs
#15,740,505
of 25,374,917 outputs
Outputs from Frontiers in immunology
#15,380
of 31,520 outputs
Outputs of similar age
#177,364
of 289,007 outputs
Outputs of similar age from Frontiers in immunology
#162
of 503 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 31,520 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one is in the 47th percentile – i.e., 47% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 289,007 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 503 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.