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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The Vitamin D Receptor and T Cell Function
|
|---|---|
| Published in |
Frontiers in immunology, January 2013
|
| DOI | 10.3389/fimmu.2013.00148 |
| Pubmed ID | |
| Authors |
Martin Kongsbak, Trine B. Levring, Carsten Geisler, Marina Rode von Essen |
| Abstract |
The vitamin D receptor (VDR) is a nuclear, ligand-dependent transcription factor that in complex with hormonally active vitamin D, 1,25(OH)2D3, regulates the expression of more than 900 genes involved in a wide array of physiological functions. The impact of 1,25(OH)2D3-VDR signaling on immune function has been the focus of many recent studies as a link between 1,25(OH)2D3 and susceptibility to various infections and to development of a variety of inflammatory diseases has been suggested. It is also becoming increasingly clear that microbes slow down immune reactivity by dysregulating the VDR ultimately to increase their chance of survival. Immune modulatory therapies that enhance VDR expression and activity are therefore considered in the clinic today to a greater extent. As T cells are of great importance for both protective immunity and development of inflammatory diseases a variety of studies have been engaged investigating the impact of VDR expression in T cells and found that VDR expression and activity plays an important role in both T cell development, differentiation and effector function. In this review we will analyze current knowledge of VDR regulation and function in T cells and discuss its importance for immune activity. |
X Demographics
The data shown below were collected from the profiles of 62 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 8 | 13% |
| Germany | 4 | 6% |
| France | 3 | 5% |
| Canada | 3 | 5% |
| Malaysia | 1 | 2% |
| Ireland | 1 | 2% |
| Spain | 1 | 2% |
| El Salvador | 1 | 2% |
| Switzerland | 1 | 2% |
| Other | 3 | 5% |
| Unknown | 36 | 58% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 54 | 87% |
| Practitioners (doctors, other healthcare professionals) | 5 | 8% |
| Scientists | 2 | 3% |
| Science communicators (journalists, bloggers, editors) | 1 | 2% |
Mendeley readers
The data shown below were compiled from readership statistics for 426 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | <1% |
| Germany | 1 | <1% |
| South Africa | 1 | <1% |
| France | 1 | <1% |
| Denmark | 1 | <1% |
| United Kingdom | 1 | <1% |
| Unknown | 419 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 62 | 15% |
| Researcher | 56 | 13% |
| Student > Ph. D. Student | 55 | 13% |
| Student > Master | 53 | 12% |
| Other | 24 | 6% |
| Other | 66 | 15% |
| Unknown | 110 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 91 | 21% |
| Biochemistry, Genetics and Molecular Biology | 61 | 14% |
| Agricultural and Biological Sciences | 58 | 14% |
| Immunology and Microbiology | 32 | 8% |
| Nursing and Health Professions | 17 | 4% |
| Other | 51 | 12% |
| Unknown | 116 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 49. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 March 2023.
All research outputs
#876,894
of 25,765,370 outputs
Outputs from Frontiers in immunology
#777
of 32,337 outputs
Outputs of similar age
#6,694
of 291,061 outputs
Outputs of similar age from Frontiers in immunology
#5
of 503 outputs
Altmetric has tracked 25,765,370 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 32,337 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 291,061 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 503 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.