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Trypanosoma cruzi Entrance through Systemic or Mucosal Infection Sites Differentially Modulates Regional Immune Response Following Acute Infection in Mice

Overview of attention for article published in Frontiers in immunology, January 2013
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Title
Trypanosoma cruzi Entrance through Systemic or Mucosal Infection Sites Differentially Modulates Regional Immune Response Following Acute Infection in Mice
Published in
Frontiers in immunology, January 2013
DOI 10.3389/fimmu.2013.00216
Pubmed ID
Authors

Juliana de Meis, Juliana Barreto de Albuquerque, Danielle Silva dos Santos, Désio Aurélio Farias-de-Oliveira, Luiz Ricardo Berbert, Vinícius Cotta-de-Almeida, Wilson Savino

Abstract

Acute Chagas disease is characterized by a systemic infection that leads to the strong activation of the adaptive immune response. Outbreaks of oral contamination by the infective protozoan Trypanosoma cruzi are frequent in Brazil and other Latin American countries, and an increased severity of clinical manifestations and mortality is observed in infected patients. These findings have elicited questions about the specific responses triggered after T. cruzi entry via mucosal sites, possibly modulating local immune mechanisms, and further impacting regional and systemic immunity. Here, we provide evidence for the existence of differential lymphoid organ responses in experimental models of acute T. cruzi infection.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 45 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 18%
Student > Master 7 16%
Student > Bachelor 6 13%
Student > Ph. D. Student 4 9%
Student > Doctoral Student 2 4%
Other 7 16%
Unknown 11 24%
Readers by discipline Count As %
Immunology and Microbiology 14 31%
Agricultural and Biological Sciences 9 20%
Medicine and Dentistry 6 13%
Biochemistry, Genetics and Molecular Biology 2 4%
Arts and Humanities 1 2%
Other 2 4%
Unknown 11 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 July 2013.
All research outputs
#19,944,091
of 25,373,627 outputs
Outputs from Frontiers in immunology
#22,573
of 31,516 outputs
Outputs of similar age
#221,304
of 288,991 outputs
Outputs of similar age from Frontiers in immunology
#240
of 503 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 31,516 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one is in the 21st percentile – i.e., 21% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 288,991 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 20th percentile – i.e., 20% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 503 others from the same source and published within six weeks on either side of this one. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.