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Tissue Specific Heterogeneity in Effector Immune Cell Response

Overview of attention for article published in Frontiers in immunology, January 2013
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Title
Tissue Specific Heterogeneity in Effector Immune Cell Response
Published in
Frontiers in immunology, January 2013
DOI 10.3389/fimmu.2013.00254
Pubmed ID
Authors

Saba Tufail, Khan Farheen Badrealam, Asif Sherwani, Umesh D. Gupta, Mohammad Owais

Abstract

Post pathogen invasion, migration of effector T-cell subsets to specific tissue locations is of prime importance for generation of robust immune response. Effector T cells are imprinted with distinct "homing codes" (adhesion molecules and chemokine receptors) during activation which regulate their targeted trafficking to specific tissues. Internal cues in the lymph node microenvironment along with external stimuli from food (vitamin A) and sunlight (vitamin D3) prime dendritic cells, imprinting them to play centre stage in the induction of tissue tropism in effector T cells. B cells as well, in a manner similar to effector T cells, exhibit tissue-tropic migration. In this review, we have focused on the factors regulating the generation and migration of effector T cells to various tissues along with giving an overview of tissue tropism in B cells.

X Demographics

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 43 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 43 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 11 26%
Student > Ph. D. Student 6 14%
Student > Master 6 14%
Other 4 9%
Student > Bachelor 3 7%
Other 9 21%
Unknown 4 9%
Readers by discipline Count As %
Agricultural and Biological Sciences 12 28%
Medicine and Dentistry 10 23%
Immunology and Microbiology 9 21%
Biochemistry, Genetics and Molecular Biology 5 12%
Pharmacology, Toxicology and Pharmaceutical Science 1 2%
Other 2 5%
Unknown 4 9%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 October 2013.
All research outputs
#19,944,091
of 25,373,627 outputs
Outputs from Frontiers in immunology
#22,573
of 31,516 outputs
Outputs of similar age
#221,304
of 288,991 outputs
Outputs of similar age from Frontiers in immunology
#240
of 503 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 31,516 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one is in the 21st percentile – i.e., 21% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 288,991 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 20th percentile – i.e., 20% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 503 others from the same source and published within six weeks on either side of this one. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.