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The Effect of Age on Thymic Function

Overview of attention for article published in Frontiers in immunology, January 2013
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (96th percentile)
  • High Attention Score compared to outputs of the same age and source (98th percentile)

Mentioned by

news
3 news outlets
blogs
1 blog
twitter
11 X users
wikipedia
1 Wikipedia page
video
1 YouTube creator

Citations

dimensions_citation
344 Dimensions

Readers on

mendeley
386 Mendeley
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Title
The Effect of Age on Thymic Function
Published in
Frontiers in immunology, January 2013
DOI 10.3389/fimmu.2013.00316
Pubmed ID
Authors

Donald B. Palmer

Abstract

Age-related regression of the thymus is associated with a decline in naïve T cell output. This is thought to contribute to the reduction in T cell diversity seen in older individuals and linked with increased susceptibility to infection, autoimmune disease, and cancer. Thymic involution is one of the most dramatic and ubiquitous changes seen in the aging immune system, but the mechanisms which underlying this process are poorly understood. However, a picture is emerging, implicating the involvement of both extrinsic and intrinsic factors. In this review we assess the role of the thymic microenvironment as a potential target that regulates thymic involution, question whether thymocyte development in the aged thymus is functionally impaired, and explore the kinetics of thymic involution.

X Demographics

X Demographics

The data shown below were collected from the profiles of 11 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 386 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 <1%
Japan 2 <1%
France 1 <1%
Portugal 1 <1%
Austria 1 <1%
Unknown 379 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 73 19%
Student > Bachelor 57 15%
Student > Master 53 14%
Researcher 42 11%
Student > Doctoral Student 18 5%
Other 61 16%
Unknown 82 21%
Readers by discipline Count As %
Agricultural and Biological Sciences 64 17%
Biochemistry, Genetics and Molecular Biology 60 16%
Immunology and Microbiology 58 15%
Medicine and Dentistry 57 15%
Unspecified 12 3%
Other 36 9%
Unknown 99 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 38. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 February 2024.
All research outputs
#1,073,329
of 25,374,647 outputs
Outputs from Frontiers in immunology
#938
of 31,516 outputs
Outputs of similar age
#8,706
of 288,991 outputs
Outputs of similar age from Frontiers in immunology
#7
of 503 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 31,516 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 288,991 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 503 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 98% of its contemporaries.