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Neuropilin-1 in Transplantation Tolerance

Overview of attention for article published in Frontiers in immunology, January 2013
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Title
Neuropilin-1 in Transplantation Tolerance
Published in
Frontiers in immunology, January 2013
DOI 10.3389/fimmu.2013.00405
Pubmed ID
Authors

Mauricio Campos-Mora, Rodrigo A. Morales, Tania Gajardo, Diego Catalán, Karina Pino-Lagos

Abstract

In the immune system, Neuropilin-1 (Nrp1) is a molecule that plays an important role in establishing the immunological synapse between dendritic cells (DCs) and T cells. Recently, Nrp1 has been identified as a marker that seems to distinguish natural T regulatory (nTreg) cells, generated in the thymus, from inducible T regulatory (iTreg) cells raised in the periphery. Given the crucial role of both nTreg and iTreg cells in the generation and maintenance of immune tolerance, the ability to phenotypically identify each of these cell populations in vivo is needed to elucidate their biological properties. In turn, these properties have the potential to be developed for therapeutic use to promote immune tolerance. Here we describe the nature and functions of Nrp1, including its potential use as a therapeutic target in transplantation tolerance.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 62 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 3%
France 2 3%
Unknown 58 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 17 27%
Student > Ph. D. Student 16 26%
Other 9 15%
Student > Bachelor 5 8%
Student > Master 4 6%
Other 5 8%
Unknown 6 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 23 37%
Immunology and Microbiology 13 21%
Biochemistry, Genetics and Molecular Biology 9 15%
Medicine and Dentistry 7 11%
Pharmacology, Toxicology and Pharmaceutical Science 1 2%
Other 2 3%
Unknown 7 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 December 2013.
All research outputs
#20,657,128
of 25,374,917 outputs
Outputs from Frontiers in immunology
#24,744
of 31,520 outputs
Outputs of similar age
#228,822
of 289,007 outputs
Outputs of similar age from Frontiers in immunology
#318
of 503 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 31,520 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one is in the 13th percentile – i.e., 13% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 289,007 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 503 others from the same source and published within six weeks on either side of this one. This one is in the 33rd percentile – i.e., 33% of its contemporaries scored the same or lower than it.